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Treatment of Delayed Hypersensitivity After Injection of Nasal Fillers.
J Cosmet Dermatol
December 2024
Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Article Synopsis
- Soft tissue filler injections, popular for cosmetic procedures, can lead to adverse reactions, particularly augmentation rhinoplasty in Asian countries due to low nasal bridges.
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Management of Acquired Aural Atresia and Stenosis: A Case Series.
Ear Nose Throat J
October 2024
Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, China.
Acquired aural atresia and aural stenosis have high recurrence rates, which are challenging for ear, nose, and throat surgeons. This study aimed to discuss the management of acquired aural atresia and aural stenosis to obtain favorable outcomes. Four representative cases of different etiologies are presented, and a related literature review was conducted.
View Article and Find Full Text PDFIdentifying DNA Variants in a Turkish Cohort with Inner Ear Anomalies.
Ear Nose Throat J
November 2024
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
To determine the genetic causes of sensorineural hearing loss (SNHL) associated with inner ear anomalies, 11 unrelated Turkish individuals diagnosed with SNHL and an inner ear anomaly using temporal bone computed tomography and inner ear magnetic resonance imaging underwent exome or whole genome sequencing to identify underlying genetic defects. None of the individuals was diagnosed with a recognized syndrome. Four of the 11 probands were homozygous for variants, , , , and .
View Article and Find Full Text PDFObjective: To evaluate and determine the prevalence of ingredients in over-the-counter (OTC) nasal sprays.
Study Design: Cross-sectional.
Setting: Retail pharmacies.
Anatomically-detailed segmented representative adult and pediatric nasal models for assessing regional drug delivery and bioequivalence with suspension nasal sprays.
Int J Pharm
December 2024
Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA, USA. Electronic address:
In vitro nasal models can potentially facilitate development and approval of nasal drug products. This study aims to evaluate the potential for using regional deposition measurements from in vitro nasal models to evaluate nasal spray performance across several products. To accomplish this, the posterior regions of six anatomically realistic nasal airway models of adult and pediatric subjects, representing Low (L), Mean (M) and High (H) posterior drug deposition (PD) for each of the two age groups, were segmented with high anatomical precision into five regions of interest.
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