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Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators.
Sci Rep
January 2025
Department of Hematology/Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia.
This study investigated the green synthesis of Zn-MnO nanocomposites via the fungus Penicillium rubens. Herein, the synthesized Zn-MnO nanocomposites were confirmed by UV-spectrophotometry with a top peak (370 nm). Transmission electron microscopy confirmed irregular particles with a spherical-like shape ranging from 25.
View Article and Find Full Text PDFModeling and optimization of surface modification process of ultrafiltration membranes by guanidine-based deep eutectic solvent.
Heliyon
January 2025
Department of Applied Chemistry, Faculty of Chemistry, Razi University, 67144-14971, Kermanshah, Iran.
Low performance and the high fouling tendency of Polyetherimide (PEI) membranes prevent their widespread commercial utility. In this study, we utilized a deep eutectic solvent (DES) as a versatile agent for surface modification of the PEI membrane using a simple and sustainable method. To attain an efficient PEI membrane, modeling and optimization of the modification condition were conducted via response surface methodology (RSM).
View Article and Find Full Text PDFAntimicrobial agents in agricultural fertilizers produced from sewage sludge - A cause for concern?
Sci Total Environ
January 2025
University of Bath, Department of Chemistry, Bath BA2 7AY, United Kingdom; Centre of Excellence in Water-Based Early Warning Systems for Health Protection, University of Bath, Bath BA25RX, United Kingdom.
The production of organic-mineral fertilizers from sewage sludge is one of the ecological options in their management. Though, pharmaceuticals and their derivatives, which accumulate in the sludge, could be a problem due to their impacts on the environment. This manuscript aimed at better understanding of risks posed by antimicrobial agents (AAs) in sludge-based fertilizers.
View Article and Find Full Text PDFUnusual Genomic and Biochemical Features of sp. nov-A Novel Bacterial Species Isolated from Anthill Soil.
Int J Mol Sci
December 2024
Faculty of Soil Science, M.V. Lomonosov Moscow State University, Leninskie Gory, 1, 119991 Moscow, Russia.
The black garden ant () is a widely distributed species across Europe, North America, and North Africa, playing a pivotal role in ecological processes within its diverse habitats. However, the microbiome associated with remains poorly investigated. In the present study, we isolated a novel species, , from the soil of the anthill.
View Article and Find Full Text PDFA new class of penicillin-binding protein inhibitors to address drug-resistant .
bioRxiv
December 2024
Venatorx Pharmaceuticals, Inc., Malvern, PA, USA.
β-Lactams are the most widely used antibiotics for the treatment of bacterial infections because of their proven track record of safety and efficacy. However, susceptibility to β-lactam antibiotics is continually eroded by resistance mechanisms. Emerging multidrug-resistant (MDR) strains possessing altered alleles (encoding PBP2) pose a global health emergency as they threaten the utility of ceftriaxone, the last remaining outpatient antibiotic.
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