By insertional mutagenesis, human cytomegalovirus recombinants deleted of each of the US6 glycoprotein family genes were isolated. A recombinant lacking IRS1, US1 through US5, and most of the US6 family was also isolated. The growth kinetics of these mutants were similar to that of the wild type. A dispensable cluster of genes was identified.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC289055 | PMC |
http://dx.doi.org/10.1128/JVI.66.4.2541-2546.1992 | DOI Listing |
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