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Mercury tolerance and bioremediation potential of mountain soil bacteria: Insights from Darjeeling, containing elevated levels of mercury.
Sci Total Environ
January 2025
Molecular Biology and Tissue Culture Laboratory, Department of Tea Science, University of North Bengal, Siliguri, West Bengal, India. Electronic address:
More and more research is now being focused on the mercury contamination of remote mountain environments. This study aimed to explore the mountain soil of Tiger Hill, Darjeeling, through the lens of its mercury tolerant bacterial microbiome to characterize regional mercury pollution and isolate strains with mercury bioremediation potential. The soil bacteria isolated from the region displayed an extreme tolerance to mercury at previously unseen levels of up to 7 mg/mL.
View Article and Find Full Text PDFBenchmarking the clinical outcomes of Healthentia SaMD in chronic disease management: a systematic literature review comparison.
Front Public Health
January 2025
AstraZeneca SpA, Milano Innovation District (MIND), Milano, Italy.
Background: Software as a Medical Device (SaMD) and mobile health (mHealth) applications have revolutionized the healthcare landscape in the areas of remote patient monitoring (RPM) and digital therapeutics (DTx). These technological advancements offer a range of benefits, from improved patient engagement and real-time monitoring, to evidence-based personalized treatment plans, risk prediction, and enhanced clinical outcomes.
Objective: The systematic literature review aims to provide a comprehensive overview of the status of SaMD and mHealth apps, highlight the promising results, and discuss what is the potential of these technologies for improving health outcomes.
User-Centred Design and Development of a Smartphone Application () for Digital Phenotyping in Ophthalmology.
Healthcare (Basel)
December 2024
Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Background: Visual impairment can significantly impact an individual's daily activities. Patients require regular monitoring, typically occurring within hospital eye services. Capacity constraints have necessitated innovative solutions to improve patient care.
View Article and Find Full Text PDFEstimating an Elephant Population Size Through Local Ecological Knowledge.
Biology (Basel)
November 2024
Anthropology and Geography, School of Law and Social Sciences, Oxford Brookes University, Oxford OX3 0BP, UK.
In planning and monitoring measures to protect wildlife in an area, it is important to have a reliable baseline estimate of population size and trends. There has been minimal published information on a small population of elephants, a keystone and endangered species, in a large area west of Etosha National Park in Namibia, known locally as the Northern Highlands. It is a highly remote, mountainous area in which it is difficult to count elephants.
View Article and Find Full Text PDFIncreasing SGLT-2 Inhibitor Prescribing Through an Integrated Case-Finding Algorithm Guided Interdisciplinary Intervention (INSPIRE).
J Am Pharm Assoc (2003)
December 2024
Endocrinologist, Senior Medical Director, Duke PHMO, Durham, NC; Professor of Medicine, Professor in Family Medicine and Community Health, Division of Endocrinology, Metabolism, Nutrition, Department of Medicine, Duke University School of Medicine, Durham, NC.
Background: Use of sodium-glucose co-transporter 2 inhibitors (SGLT-2 inhibitors) falls short of their cardiorenal protective benefits. Patient and provider-level barriers hinder the adoption of these life-saving medications. Innovative practices to provide primary care providers (PCP) with added clinical-decision support via a dedicated remote interdisciplinary diabetes rounds (IDR) team could promote SGLT-2 inhibitor selection.
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