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Comparing carbon agronomic footprint and sequestration in Central American coffee agroforestry systems and assessing trade-offs with economic returns.
Sci Total Environ
January 2025
CATIE, Centro Agronómico Tropical de Investigación y Enseñanza, Turrialba 30501, Costa Rica.
Agricultural systems are both emitters of greenhouse gases and have the potential to sequester carbon, especially agroforestry systems. Coffee agroforestry systems offer a wide range of intensities of use of agricultural inputs and densities and management of shade trees. We assessed the agronomic carbon footprint (up to farm gate) and modelled the carbon sequestration of a range of coffee agroforestry systems across 180 farms in Costa Rica and Guatemala.
View Article and Find Full Text PDFPlasma anti-CD4 IgG levels are associated with poor immune recovery in people with HIV initiating antiretroviral therapy.
AIDS
February 2025
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY.
A segment of people with HIV on effective antiretroviral therapy (ART) continue to experience poor immune recovery, leaving them at heightened risk of non-AIDS-defining events (NAEs). The production of anti-CD4 IgG autoreactive antibodies is suggested as one contributing mechanism to these complications. Here, we found that plasma anti-CD4 levels do not discriminate immunological responders from nonresponders nor predict the occurrence of NAEs, suggesting it is unlikely a contributing immunopathological factor associated with these complications.
View Article and Find Full Text PDFHip-Spine Relationship in Femoroacetabular Impingement: Does Hip Arthroscopy Affect Pelvic Mobility?
Clin Orthop Relat Res
December 2024
Naval Medical Center San Diego, San Diego, CA, USA.
Background: Femoroacetabular impingement (FAI) is a well-recognized cause of hip pain in adults. The hip-spine relationship between the femur, pelvis, and lumbosacral spine has garnered recent attention in hip arthroplasty. However, the hip-spine relationship has not been well described in patients with FAI.
View Article and Find Full Text PDFUpdating an HIV Knowledge Questionnaire With Pre-exposure Prophylaxis Through Expert Opinions in the United States Using Delphi Methodology: A Qualitative Study.
J Assoc Nurses AIDS Care
January 2025
Se Hee Min, PhD, RN, is an Assistant Professor, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA.
Our study was designed to update the HIV Knowledge Questionnaire by incorporating pre-exposure prophylaxis (PrEP) knowledge questions, as previous HIV knowledge tools lack this focus. Four rounds of Delphi surveys were conducted with 47 expert participants, each with extensive HIV-related expertise (mean experience: 18.94 years).
View Article and Find Full Text PDFPatient stratification by genetic risk in Alzheimer's disease is only effective in the presence of phenotypic heterogeneity.
PLoS One
January 2025
Washington University School of Medicine, NeuroGenomics and Informatics Center, St. Louis, MO, United States of America.
Case-only designs in longitudinal cohorts are a valuable resource for identifying disease-relevant genes, pathways, and novel targets influencing disease progression. This is particularly relevant in Alzheimer's disease (AD), where longitudinal cohorts measure disease "progression," defined by rate of cognitive decline. Few of the identified drug targets for AD have been clinically tractable, and phenotypic heterogeneity is an obstacle to both clinical research and basic science.
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