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http://dx.doi.org/10.1136/bmj.1.4856.245 | DOI Listing |
Int J Biol Macromol
January 2025
College of Pharmaceutical Science, Dali University, Dali 671000, China; International Joint Laboratory for the Development and Utilization of Traditional Chinese Medicine Resources in Yunnan Province, Baoshan 678300, Dali 671000, China. Electronic address:
Ficus carica (F. carica) is a well-known medicinal and edible plant with high nutritive values. Polysaccharides are the primary and important bioactive components in F.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
State Key Laboratory of Integration and Innovation of Classical formula and Modern Chinese Medicines, National Chinmedomics Research Center, National TCM Key Laboratory of Serum Pharmacochemistry, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040, China; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau. Electronic address:
Acanthopanax senticosus, a celebrated herbal remedy, has been cherished in China for its health-promoting properties for over two millennia. The plant's key bioactive constituent, A. senticosus polysaccharide (ASPS), has recently attracted significant interest due to its exceptional biological activities.
View Article and Find Full Text PDFFoods
December 2024
State Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine, No.1899 Meiling Road, Nanchang 330103, China.
Hance has a medicinal history of thousands of years in treating cough, diabetes, and gastrointestinal system diseases, and it is also a medicine food homology (MFH) plant in China. To evaluate the pharmacological activities of polysaccharides from the rhizomes of , polysaccharides were initially obtained by hot-water extraction and the ethanol precipitation method. A homogenous polysaccharide designated as AOP-w was isolated by a DE-52 column.
View Article and Find Full Text PDFJ Diabetes Metab Disord
December 2024
Department of Ophthalmology, School of Medicine, Vali-E-Asr Hospital, Zanjan University of Medical sciences, Zanjan, Iran.
Objectives: Diabetic retinopathy (DR), an earnest complication of diabetes, is one of the most common causes of blindness worldwide. This study aimed to investigate the altered metabolites in the serum of non-DR (NDR) and DR including non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR) subjects.
Methods: In this study, the 1HNMR platform was applied to reveal the discriminating serum metabolites in three diabetic groups based on the status of their complications: T2D or NDR ( = 15), NPDR, ( = 15), and PDR ( = 15) groups.
Carbohydr Polym
January 2025
Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Diabetic foot ulcers (DFUs) as a nonhealing wound remain a clinical challenge, and the development of pro-healing and cost-effective drugs is in urgent need. Herein, we reported a novel galactosylated glycosaminoglycan (GAG) from the snail Helix lucorum, as an effective pro-healing compound. The snail GAG is composed of a heparan sulfate-like main chain and galactose side chains at C-3 of GlcNAc residue.
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