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Endocrine Emergencies.
Prim Care
September 2024
Department of Medicine, Endocrinology Division, UPMC Center for Endocrinology & Metabolism, University of Pittsburgh Medical College, 3601 5th Avenue, Falk Suite 3B, Pittsburgh, PA 15213, USA.
Endocrine emergencies encompass a group of conditions that occur when hormonal deficiency or excess results in acute presentation. If these endocrine disorders are not rapidly identified or if specific treatment is delayed, significant complications or even death may occur. This article outlines the basics of endocrine emergencies involving the thyroid, parathyroid, pituitary, pancreas, and adrenal glands.
View Article and Find Full Text PDFTwo synchronous paraneoplastic endocrine syndromes in a 53-year-old male with broadly metastatic widely invasive Hürthle cell carcinoma.
Endocrinol Diabetes Metab Case Rep
January 2024
Department of Pathology, Kaiser Foundation Health Plan of Colorado, Denver, Colorado, USA.
Summary: Unlike medullary thyroid carcinomas, follicular cell-derived thyroid malignancies have rarely been associated with paraneoplastic endocrine syndromes. An ultrarare case of a middle-aged man with heavily treated broadly metastatic radioactive iodine-refractory widely invasive Hürthle cell carcinoma (HCC) of the thyroid with two synchronous paraneoplastic endocrine syndromes, T3 thyrotoxicosis and hypercalcemia of malignancy, is discussed here. The levothyroxine-induced T3 thyrotoxicosis was a gradual process that became more noticeable as the tumor burden, refractory to different modalities of therapy, expanded.
View Article and Find Full Text PDFPostoperative Hypocalcemia in Hyperthyroid Patients: The Parathyroids Aren't Always to Blame.
J Surg Res
August 2023
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address:
Introduction: Hypocalcemia is commonly reported after thyroidectomy and has multiple possible etiologies including: parathyroid devascularization, reactive hypoparathyroidism from relative hypercalcemia in thyrotoxicosis, and abrupt reversal of thyrotoxic osteodystrophy. In patients that are actively hyperthyroid and undergoing thyroidectomy, it is not known how many experience hypocalcemia from nonhypoparathyroidism etiologies. Therefore, our aim was to examine the relationship among thyrotoxicosis, hypocalcemia, and hypoparathyroidism.
View Article and Find Full Text PDFRare Presentation of a Common Disease: Graves' Thyrotoxicosis Presented With Non-parathyroid Hypercalcemia and Jaundice.
Cureus
February 2023
Department of Endocrinology, Diabetes and Metabolism, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh, SAU.
Article Synopsis
- - Graves' disease is an autoimmune condition that leads to hyperthyroidism, exhibiting symptoms such as tremors, weight loss, and heat intolerance, while also potentially causing liver issues.
- - A rare case highlighted involves Graves' thyrotoxicosis where the patient experienced severe cholestasis and high calcium levels, with thorough tests for liver problems coming back negative.
- - The patient improved after treatment with methimazole, leading to better clinical and biochemical outcomes.
Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma.
Asia Ocean J Nucl Med Biol
January 2022
Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- * A 53-year-old woman with a thyroid disorder was found to have hypercalcemia and elevated parathyroid hormone levels, leading to imaging tests that indicated a parathyroid adenoma.
- * Further testing revealed the issue was actually a toxic thyroid adenoma, and after receiving radioactive iodine treatment, her thyrotoxicosis and calcium levels returned to normal.
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