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A single-centre randomised controlled trial comparing the standard method and target-controlled infusion as a method of administering cefoxitin, which is used to prevent surgical site infections in colorectal surgical patients: study protocol.
Trials
January 2025
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Korea.
Background: Prophylactic parenteral administration of antibiotics is strongly recommended to prevent surgical site infection (SSI). Cefoxitin is mainly administered intravenously in colorectal surgery. The current standard method for administering prophylactic antibiotics in adults is to administer a fixed dose quickly before skin incision.
View Article and Find Full Text PDFElectrical conductivity in the mantle transition zone beneath eastern Central Asian Orogenic Belt revealed by geomagnetic signals.
Sci Rep
January 2025
School of Safety Engineering and Emergency Management, Shijiazhuang Tiedao University, Shijiazhuang, 050043, China.
In the eastern segment of the Central Asian Orogenic Belt (CAOB), there is widespread volcanic magma activity. However, there is still considerable controversy over the formation mechanisms and material sources of these volcanoes. The mantle transition zone (MTZ), as a necessary channel for the upward and downward movement of mantle material and energy exchange may provide crucial constraints on the dynamic mechanisms of volcanic activity.
View Article and Find Full Text PDFGOLD grade-specific characterization of COPD in the COSYCONET multi-center trial: comparison of semiquantitative MRI and quantitative CT.
Eur Radiol
January 2025
Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.
Objectives: We hypothesized that semiquantitative visual scoring of lung MRI is suitable for GOLD-grade specific characterization of parenchymal and airway disease in COPD and that MRI scores correlate with quantitative CT (QCT) and pulmonary function test (PFT) parameters.
Methods: Five hundred ninety-eight subjects from the COSYCONET study (median age = 67 (60-72)) at risk for COPD or with GOLD1-4 underwent PFT, same-day paired inspiratory/expiratory CT, and structural and contrast-enhanced MRI. QCT assessed total lung volume (TLV), emphysema, and air trapping by parametric response mapping (PRM, PRM) and airway disease by wall percentage (WP).
Leveraging Multivalent Assembly towards High-Temperature Liquid-Phase Phosphorescence.
Angew Chem Int Ed Engl
January 2025
Ningbo Institute of Materials Technology and Engineering CAS: Chinese Academy of Sciences Ningbo Institute of Materials Technology and Engineering, Key Laboratory of Advanced Marine Materials, Ningbo Institute of Materials Technology and Engineering, CHINA.
High-temperature phosphorescence (HTP) materials have attracted considerable attention owing to their expanded application prospects, whereas they still suffer from severe deactivation in polar media, limiting their reliability and utility. Here, we present an efficient multivalent assembly strategy to achieve high-temperature liquid-phase phosphorescence (HTLP). The supramolecular assembly of multivalent modules leads to extremely robust hydrogen-bonding networks, which firmly immobilize the organic phosphors and protect triplet excitons from annihilation in high-temperature polar media, resulting in excellent HTLP emission.
View Article and Find Full Text PDFValidation of immersion pre-cooling and drip sanitation standard operating procedures on weight, temperature, microbiological quality, and safety of chicken carcasses.
J Food Prot
January 2025
Food Microbiology Laboratory, Veterinary Medicine Department, Universidade Federal do Norte do Tocantins, Araguaína, Tocantins, Brazil. Electronic address:
This study aims to validate sanitation standard operating procedures (SSOP) of the pre-cooling system in two immersion stages with different temperatures followed by dripping for 3 minutes. The variables evaluated were temperature, weight, microbiological quality, and safety of chicken carcasses. Groups of indicator microorganisms were quantified and the occurrence of Salmonella spp.
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