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Identification and functional analysis of a novel L-type lectin (NdLTL1) from Neocaridina denticulata sinensis.
Fish Shellfish Immunol
January 2025
School of Life Sciences/Hebei Basic Science Center for Biotic Interaction, Hebei University, Baoding, 071002, China; Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China. Electronic address:
This study investigates an L-type lectin, NdLTL1, derived from Neocaridina denticulata sinensis, emphasizing its role in immune defense through carbohydrate binding and bacterial agglutination. Bioinformatics analysis identified 179 lectin sequences, leading to subsequent investigations into the structure and function of NdLTL1. The open reading frame (ORF) of NdLTL1 spans 966 bp and encodes a protein consisting of 321 amino acids (36.
View Article and Find Full Text PDFEfficacy of hyperimmunized egg yolk antibodies (IgY) against Campylobacter jejuni: In Vitro and In Vivo evaluations.
Poult Sci
January 2025
Prestage Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27695-7608. Electronic address:
Campylobacter infections are a prevalent cause of diarrheal disease in humans and are the most significant zoonotic pathogens worldwide. Human campylobacteriosis is generally via ingestion of contaminated poultry products. However, based on recent studies chicken egg yolk antibody (IgY) powder has great potential to reduce the cecum load of Campylobacter jejuni (C.
View Article and Find Full Text PDFAn Epidemiological Study on in Tibetan Yaks from the Qinghai-Tibet Plateau Area in China.
Animals (Basel)
December 2024
College of Animal Science, Tibet Agricultural and Animal Husbandry University, Nyingchi 860000, China.
is an important foodborne pathogen that can cause a range of illnesses in humans; it has also been a key focus for monitoring in the field of public health, including gastroenteritis, sepsis, and arthritis, and can also cause a decline in egg production in poultry and diarrhea and abortion in livestock, leading to death in severe cases, resulting in huge economic losses. This study aimed to investigate the isolation rate, antimicrobial resistance, serotypes, and genetic diversity of isolated from yak feces in various regions on the Qinghai-Tibet Plateau. A total of 1222 samples of yak dung were collected from major cities in the Qinghai-Tibet Plateau area, and the sensitivity of the isolated bacteria to 10 major classes of antibiotics was determined using the K-B paper disk diffusion method for drug susceptibility.
View Article and Find Full Text PDFEffectiveness of the RB51 vaccine in controlling brucellosis in adult beef cows.
Front Vet Sci
November 2024
MSD Animal Health, São Paulo, São Paulo, Brazil.
Introduction: The aim of this study was to compare the effectiveness of brucellosis control and reproductive performance using one or two doses of RB51 strain vaccine.
Methods: This experiment was conducted at two commercial beef farms (A, = 477; and B, = 673), which were selected due to their records of endemic brucellosis and a prevalence of 6 to 8% of seropositive cows. An initial serology screening (Day 0) was carried out in all cows using the Rose Bengal test (RB), and presumptive positive results were re-evaluated using a slow agglutination test with 2-mercaptoethanol (2-ME).
Weakly Supervised Multiple Instance Learning Model With Generalization Ability for Clinical Adenocarcinoma Screening on Serous Cavity Effusion Pathology.
Mod Pathol
November 2024
Department of Pathology, the First Affiliated Hospital, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. Electronic address:
Article Synopsis
- Accurate and rapid screening of adenocarcinoma cells in serous cavity effusion is essential for diagnosing metastatic tumors and initiating timely treatment, but this process can be challenging for pathologists.
- Fixed agglutination cell blocks enhance diagnostic sensitivity by analyzing larger effusion volumes, while advancements like whole slide imaging and artificial intelligence aim to support pathologists in improving diagnostic accuracy and efficiency.
- This study introduces a novel weakly supervised deep learning model that, combined with cell block technology, demonstrates high performance in screening serous adenocarcinoma, reduces pathologist workload, and shows potential for clinical applications, along with creating the first public datasets for further research.
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