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Evaluation of tolerability and skin changes after application of topical antiaging products based on Sibanid SG®, plant stem cells and regenerative and biostimulating active ingredients.
G Ital Dermatol Venereol
February 2019
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Background: The oxidative stress, the UV radiations, the matrix metalloproteinases (MMPs) and the hyaluronidase enzyme play an extremly important role in skin aging processes, leading an increasing production of elastase, collagenase and hyaluronidase that brings to degradation of collagen, elastin and hyaluronic acid respectively. They are responsible to provide strength, elasticity and moisture to the skin. Innovative devices were developed based on the effective ingredients against hyaluronidase and MMP.
View Article and Find Full Text PDFScar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure.
Photomed Laser Surg
May 2017
1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy .
Objective: A study was established to objectively assess the effects of low-intensity electromagnetic and electric stimulation plus negative pressure on mature scars.
Background: Radiofrequency plus negative pressure therapy demonstrated a favorable reorganization and regeneration of the collagen and elastic fibers and was proposed for the treatment of cellulitis and skin stretch marks.
Methods: Twenty-six mature scars in 20 Caucasian patients (15 females and 5 males) were enrolled in the study.
Contribution of breast skin elastometry measurement in breast augmentation surgery: A pilot study evaluating the correlation between skin elasticity and nipple-to-inframammary fold distance.
J Plast Reconstr Aesthet Surg
September 2015
Plastic and Reconstructive Surgery Unit, University Hospital of Marseille, France.
Long-term in vivo assessment of bioengineered skin substitutes: a clinical study.
J Tissue Eng Regen Med
April 2015
Department of Clinical Surgical Diagnostic and Paediatric Sciences, University of Pavia, Italy; Advanced Technologies for Regenerative Medicine and Inductive Surgery Research Centre, University of Pavia, Italy; Plastic and Reconstructive Surgery Unit, Salvatore Maugeri Research and Care Institute, Pavia, Italy.
The aim of the study was an objective in vivo assessment of skin properties after reconstruction with two artificial dermal substitutes, Integra® and Hyalomatrix®. Twenty-seven patients underwent reconstruction of 36 skin-loss sites with full-thickness skin graft, split-thickness skin graft, Hyalomatrix® bioengineered skin substitute and sequential split-thickness skin graft and Integra® bioengineered skin substitute and sequential split-thickness skin graft. Objective assessments were carried out using three instrumental devices: Multi Probe Adapter System MPA; 22 MHz ultrasound skin scan; and Primos Pico for a three-dimensional (3D) skin scan.
View Article and Find Full Text PDFEnhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
Drug Dev Ind Pharm
October 2014
Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Seville, Seville , Spain .
Trans-resveratrol, a polyphenol extracted from Vitis vinifera, has different beneficial effects following its administration on the skin. Here the potential use of binary systems to enhance in vitro and in vivo activity of trans-resveratrol was investigated. Thus the aqueous solubility of trans-resveratrol was investigated in the presence of growing concentrations of polyethylene glycol (PEG) or β-cyclodextrin (βCD) as solubilizing excipients.
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