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The value of quantitative muscle ultrasound in monitoring muscle and fascia inflammatory activity in juvenile dermatomyositis patients.
Quant Imaging Med Surg
December 2024
Department of Rheumatology, Children's Hospital Affiliated with Capital Institute of Pediatrics, Beijing, China.
Background: Currently, the activity of juvenile dermatomyositis (JDM) is mainly assessed based on clinical manifestations, creatine kinase (CK) level, and magnetic resonance imaging (MRI), but certain limitations arise in these approaches for children. Thus, this cross-sectional study aimed to explore the value of ultrasound in evaluating muscle inflammation via the dynamic analysis of muscle ultrasound characteristics in children with active or stable JDM.
Methods: The data of a group of children who were diagnosed with JDM and admitted to the Rheumatology and Immunology Department of the Capital Pediatric Research Institute Children's Hospital between June 2022 and November 2023, and a normal control group were collected.
Ovarian tissue cryopreservation for an 8 year old girl after hematopoietic stem cell transplantation in China: case report and literature review.
Gynecol Endocrinol
December 2024
Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.
Article Synopsis
- * A case study involves an 8-year-old girl undergoing a second HSCT for dermatomyositis who successfully had her ovarian tissue cryopreserved (OTC) prior to the procedure, with measurable ovarian function as indicated by hormonal assessments and ultrasound results.
- * The report emphasizes the importance of consulting fertility preservation experts post-HSCT for those who missed pre-HSCT preservation, highlighting OTC as a viable option for protecting fertility in women after HSCT.
Article Synopsis
- Muscle relaxants like rocuronium can be risky for patients with conditions such as polymyositis, particularly in cases that are not fully controlled.
- This report outlines a case where a 27-year-old woman with controlled polymyositis underwent minor surgery, requiring careful monitoring of her neuromuscular function during and after the use of rocuronium and sugammadex.
- Findings suggest prolonged muscle relaxation effects, attributed to decreased muscle volume in polymyositis patients, highlighting the need for close supervision in such surgical settings.
The Lack of a Durable Response to Tofacitinib in Anti-PL-12 Anti-synthetase Syndrome With Progressive Interstitial Pneumonitis.
Cureus
December 2023
Rheumatology, White River Health, Batesville, USA.
We discuss a case of a 48-year-old female with anti-PL-12 anti-synthetase syndrome. She presented with dermatitis and myositis and developed rapidly progressive interstitial lung disease (ILD) while on prednisone and azathioprine, which responded dramatically to the addition of tofacitinib. However, the patient later developed arthritis, worsening skin disease, cutaneous vasculitis, and worsening ILD with corticosteroid reduction.
View Article and Find Full Text PDFDiagnosis of neuropsychiatry disorder in patients with anti-MDA5 antibody dermatomyositis: A case report.
Heliyon
December 2023
Department of Rheumatology, the Second Affiliated Hospital of Dalian Medical University, China.
Anti-melanoma differentiation-associated gene 5 (MDA5) dermatomyositis (DM) is a rare disease that can be easily misdiagnosed. Anti-MDA5 dermatomyositis is a subtype of DM. It is distinguished by the presence of significant mucocutaneous characteristics, palmar papules, panniculitis, interstitial lung disease (ILD), and clinically amyopathic dermatomyositis (CADM).
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