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Red cell antibodies or noise? A case series on reactivity against the ingredients in column matrix.
Asian J Transfus Sci
November 2023
Department of Transfusion Medicine, Tata Medical Center, Kolkata, West Bengal, India.
Noise in the immunohematological investigations can be described as a false reactivity of red blood cells (RBCs) in serologic testing that is not related to the interaction of RBC antigens and antibodies that the test system is intended to detect. These false-positive reactions can cause confusion during the cross-matching and RBC antibody screening and may result in delays in patient transfusion. Although these antibodies are predominantly clinically insignificant, proper laboratory work-up is indicated to avoid misidentification of a clinically significant antibody as a noise.
View Article and Find Full Text PDFPilot study to understand and compare challenges being faced in reporting of transfusion reactions in various types of blood banks enrolled under Haemovigilance Programme of India.
Asian J Transfus Sci
May 2023
Haemovigilance Programme of India, National Institute of Biologicals, Noida, Uttar Pradesh, India.
Background: Hemovigilance has become one of the important quality check systems of blood transfusion process, but under/non-reporting of transfusion-associated adverse reactions despite the presence of reporting systems emphasize the need to understand the challenges being faced in active reporting of adverse transfusion reactions.
Aim: To identify and document the possible factors leading to under-reporting and impacting the quality of blood transfusion reactions being submitted under Haemovigilance Programme of India (HvPI).
Settings And Design: This was a cross-sectional, observational type study, carried out in six blood banks, two each of government, private, and stand-alone sectors in Delhi National Capital Region enrolled under HvPI.
Safety of COVID-19 Vaccines in Patients With Multiple Sclerosis: A Cross-Sectional Study From a Tertiary Rehabilitation Center in Saudi Arabia.
Cureus
December 2024
Internal Medicine, Sultan Bin Abdulaziz Humanitarian City, Riyadh, SAU.
Background The safety and adverse effects (AEs) associated with approved COVID-19 vaccines in individuals with multiple sclerosis (MS) require further examination, particularly as there is limited information available for MS patients in Saudi Arabia. This study sought to investigate the reported AEs of COVID-19 vaccines among MS patients admitted to a major rehabilitation center in Saudi Arabia. Methods A cross-sectional analysis was conducted from January 2023 to March 2024 at Sultan Bin Abdulaziz Humanitarian City (SBAHC) in Riyadh.
View Article and Find Full Text PDFRobotic Rigor: Validity of the Kinarm End-Point Robot Visually Guided Reaching Test in Multiple Sclerosis.
Arch Rehabil Res Clin Transl
December 2024
Recovery and Performance Laboratory, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.
Objective: To determine whether robotic metrics: (1) correlate with the Nine-Hole Peg Test (9HPT; good convergent validity); and (2) differentiate between those self-reporting "some hand problems" versus "no hand problems" (good criterion validity).
Design: Cross-sectional validation analyses.
Setting: Rehabilitation research laboratory located within a hospital.
Easily Accessible and Solution-Stable Ni(0) Precatalysts for High-Throughput Experimentation.
Chemistry
January 2025
University of Victoria, Chemistry, 3800 Finnerty Rd, V8P 5C2, Victoria, CANADA.
We report the synthesis, characterization, and catalytic applications of N,N'-diaryl diazabutadiene (DAB) Ni(0) complexes stabilized by alkene ligands. These complexes are soluble and stable in several organic solvents, making them ideal candidates for in situ catalyst formation during high-throughput experimentation (HTE). We used HTE to evaluate these Ni(0) precatalysts in a variety of Suzuki and C-N coupling reactions, and they were found to have equal or better performance than the still-standard Ni(0) source, Ni(COD)2.
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