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[Clinical characteristics and therapy of neurosyphilis in patients who are negative for human immunodeficiency virus].
Srp Arh Celok Lek
January 2000
Institute of Neurology, Clinical Centre of Serbia, Belgrade.
Introduction: Neurosyphilis is still a significant medical problem in developing countries and its occurrence in HIV infection is the reason for a growing number of new cases in developed countries [1-4]. Personality changes are the commonest symptom of late neurosyphilis [5]. Neurologic deficits are usually due to syphilitic vasculitis with lacunar infarctions [6].
View Article and Find Full Text PDF[Immunoblotting for the serodiagnosis of syphilis. A candidate to replace the Nelson-Mayer test].
Ann Pharm Fr
January 1999
Centre de Biologie Médicale Spécialisée, Institut Pasteur, Paris.
The lipid antigens used in the Bordet-Wassermann and prepared by Landsteiner and Marie for syphilis tests from 1909 to 1949 were non specific but have certain common features with the spirochete body. For more than forty years the Bordet-Wassermann reaction, associated with flocculation (Kahn) or agglutination (Kline-VDRL) was used to detect cases of tremonematosis despite frequent false positives reactions due to other infections. In 1949, the Nelson and Mayer test was introduced.
View Article and Find Full Text PDF[The significance of Karl Landsteiner's works for syphilis research].
Wien Klin Wochenschr
June 1991
Ludwig-Boltzmann-Institut für dermato-venerologische Serodiagnostik, Krankenhaus der Stadt Wien-Lainz.
On January 7th 1905, more than five months before the detection of T. pallidum, Karl Landsteiner began his work on syphilis research together with notable members of the Viennese School of Medicine, namely Ernest Finger, Rudolf Müller, Viktor Mucha, Otto Pötzl and others. Extensive animal experiments led to the formulation of the Finger-Landsteiner Law and provided the basic facts for the Jadasson-Lewandowsky Law.
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