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The Impact of Lifestyle Intervention Programs on Long-Term Cardiac Event-Free Survival in Patients With Established Coronary Artery Disease.
Cureus
December 2024
Internal Medicine, Services Hospital Lahore, Lahore, PAK.
Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, necessitating comprehensive approaches for its management. This systematic review evaluates the long-term impact of structured lifestyle intervention programs on cardiac event-free survival in patients with established CAD. A total of eight studies, including randomized controlled trials (RCTs) and prospective cohort studies, were analyzed, encompassing diverse interventions such as cardiac rehabilitation, dietary modifications, exercise programs, and psychosocial support.
View Article and Find Full Text PDFpH is an important physiological parameter within organisms, playing a crucial role in functional activities in cells and tissues. Among various pH sensing methods, optical fiber pH sensors have gained a wide attention due to their unique advantages. However, current silica optical fiber-based pH sensors face some challenges such as weak biocompatibility, low biological safety, complex or unstable surface modification.
View Article and Find Full Text PDFNonlinear emission phenomena observed in transition metal dichalcogenides (TMDCs) have significantly advanced the development of robust nonlinear optical sources within two-dimensional materials. However, the intrinsic emission characteristics of TMDCs are inherently dependent on the specific material, which constrains their tunability for practical applications. In this study, we propose a strategy for the selective enhancement and modification of second-harmonic generation (SHG) emission in a multilayer WS flake through the implementation of a silicon (Si)-based circular Bragg grating (CBG) structure positioned on an Au/SiO substrate.
View Article and Find Full Text PDFHollow mesoporous silica nanoparticles for drug formulation and delivery: Opportunities for cancer therapy.
Colloids Surf B Biointerfaces
January 2025
Shaanxi Key Laboratory of Catalysis, School of Chemistry and Environment Science, Shaanxi University of Technology, No.1 East 1st Ring Road, Hanzhong, Shaanxi 723001, PR China.
The advantages of large surface area, high volume ratio, good biocompatibility, and controllable surface functionalization make hollow mesoporous silica nanoparticles (HMSNs) an ideal drug carrier. HMSNs can achieve high efficiency, targeting, and controlled release by adjusting the microstructure and surface modification of its particles, which makes it broad application prospects in the field of medical therapy, especially in cancer therapy. Numerous studies have shown that preparation method, shape, particle size, hollow inner diameter, aperture and wall thickness of the HMSNs, the characteristics of the drugs, the interaction between the drugs and the carriers, and the external environment all closely affect the drug delivery, release, and efficacy.
View Article and Find Full Text PDFEngagement With an Internet-Administered, Guided, Low-Intensity Cognitive Behavioral Therapy Intervention for Parents of Children Treated for Cancer: Analysis of Log-Data From the ENGAGE Feasibility Trial.
JMIR Form Res
January 2025
CIRCLE - Complex Intervention Research in Health and Care, Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Background: Parents of children treated for cancer may experience psychological difficulties including depression, anxiety, and posttraumatic stress. Digital interventions, such as internet-administered cognitive behavioral therapy, offer an accessible and flexible means to support parents. However, engagement with and adherence to digital interventions remain a significant challenge, potentially limiting efficacy.
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