AI Article Synopsis
- A 64-year-old male presented with right lower limb pain and weakness, leading to the discovery of cervical and dorsal tumors, as well as lumbosacral infiltration.
- Histological examination indicated a diagnosis of meningeal melanocytoma, a rare tumor previously misclassified as pigmented meningioma due to its similarities.
- Unlike previous cases with solitary tumors, this review notes that multiple meningeal melanocytomas can occur, with treatment options including surgery, radiotherapy, and chemoimmunotherapy.
Article Abstract
In a 64-year-old male with pain and weakness of the right lower limb, investigations disclosed a cervical tumor, several dorsal tumors, and tumoral infiltration of the lumbosacral area. Histological and, above all, immunohistochemical and ultrastructural features were suggestive of meningeal melanocytoma. Before the use of immunohistochemical and electron microscopy techniques, meningeal melanocytoma was designated by the term pigmented meningioma because its histological features bear some resemblance to those of meningioma. However, only a few cases of meningeal melanocytoma have been documented by immunohistochemistry and electron microscopy. Previously reported patients with meningeal melanocytoma had solitary tumors. In contrast, a review of the literature showed that multiple intraspinal or intraspinal and intracranial meningiomas are not exceptional, although meningiomatous infiltration is considerably less frequent. Treatment of such cases rests on surgery, radiotherapy, and chemoimmunotherapy.
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