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A New Conceptual Framework for Enhancing Vaccine Efficacy in Malnourished Children.
J Multidiscip Healthc
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Background: Malnourished children in low- and middle-income countries (LMICs) often exhibit reduced vaccine efficacy, particularly for oral vaccines like polio and rotavirus, due to impaired immune responses. Nutritional deficiencies, such as in vitamin A and zinc, along with environmental factors like poor sanitation, exacerbate this issue. Existing research has explored the individual impacts of malnutrition on vaccine outcomes, but a comprehensive framework that integrates nutritional, immune, and environmental factors has been lacking.
View Article and Find Full Text PDFImplementation of Mass Drug Administration for Lymphatic Filariasis in Madagascar: The Progress, Effectiveness and Financial Savings of Integrating into an Existing Polio Campaign.
Res Rep Trop Med
December 2024
Madagascar Country Office, World Health Organization, Antananarivo, Madagascar.
Introduction: This paper presents (a) the progress made towards achieving the 2023 Lymphatic Filariasis (LF) Mass Drug Administration (MDA) campaign goals, (b) the estimated financial savings resulting from integrating LF MDA into Polio immunization campaigns, and (c) the best practices, challenges, and recommendations.
Methods: In 2023, 21,336,057 people in 83 districts were affected by LF and required Preventive Chemotherapy (PC). The National NTD Control Programme (NTDCP) conducted three phases of LF MDA campaigns in those districts.
Confidence in the efficacy of routine vaccines after the COVID-19 pandemic: a cross-sectional web-based study.
BMC Public Health
December 2024
Pharmaceutics and Industrial Pharmacy Department, College of Pharmacy, Taif University, Taif, 21944, Saudi Arabia.
Background: There is limited data that assessed the changes in public confidence in routine childhood and adult vaccines after Corona Virus Disease-2019 (COVID-19) pandemic. We, therefore, assessed these changes and the reasons; if any; for these changes and measured the impact of COVID-19 on peoples' thoughts regarding routine vaccinations in Saudi Arabia.
Methods: We undertook a cross-sectional online study in Saudi Arabia from November 2023 to April 2024.
The article is devoted to the problems of implementation of the WHO Global Polio Eradication Initiative. The influence of the features of poliovirus infection and poliovirus vaccines on the course of the program, its successes and difficulties is considered, the issue of possibility of eradication this infection is discussed.
View Article and Find Full Text PDFDr. Thomas Francis Jr.: A Legacy of Vaccine Innovation and Public Health Advancement.
Cureus
November 2024
Central Research Facility, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to Be University), Pune, IND.
Dr. Thomas Francis Jr. was an American physician, virologist, and epidemiologist who was a professor of epidemiology at the University of Michigan from 1941 to 1969.
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