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We herein report a rare case of simultaneous intrauterine molar pregnancy and tubal pregnancy. A woman of childbearing age who had never been pregnant underwent an ultrasound examination 70 days after the onset of menopause. She had a history of ovulation induction.

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[First-line management of infertile couple. Guidelines for clinical practice of the French College of Obstetricians and Gynecologists 2022].

Gynecol Obstet Fertil Senol

May 2024

Service d'assistance médicale à la procréation, pôle Femmes-Parents-Enfants, hôpital de la Conception, AP-HM, 147, boulevard Baille, 13005 Marseille, France; IMBE, CNRS, IRD, Aix-Marseille université, Avignon université, Marseille, France. Electronic address:

Article Synopsis
  • The updated clinical practice guidelines aim to improve the first-line management of infertility in couples by revisiting existing recommendations based on recent research.
  • A systematic review was conducted by expert working groups on five major themes, resulting in 28 PICO-formulated questions addressing both male and female infertility assessments, environmental factors, ovulation induction, and reproductive surgery techniques.
  • Key recommendations include tailored fertility evaluations based on the woman's age, specific tests for both partners, and the dismissal of certain outdated procedures, with an emphasis on evidence-based approaches to optimize infertility treatment.
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Article Synopsis
  • Ectopic pregnancy is a major cause of maternal mortality during the first trimester, with the fallopian tube being the most common site of occurrence.
  • Surgical options include salpingotomy (partial removal of the affected tube) and salpingectomy (complete removal), with persistent ectopic pregnancies more likely after salpingotomy.
  • In the presented case, a patient underwent a right salpingectomy but returned with abdominal pain and high beta-HCG levels; a second surgery revealed ectopic tissue that was subsequently treated successfully with a single dose of methotrexate.
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Bilateral ectopic pregnancy is very rare. Although the frequency of ectopic bilateral pregnancy has increased with the advent of medically assisted procreation, spontaneous bilateral tubal pregnancies remain rare. Early detection of this type of ectopic pregnancy is important to prevent maternal mortality and morbidity.

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Ectopic pregnancy is a gynecological emergency. The hCG level, the clinical presentation and the ultrasound remain the key steps for the diagnosis. The criteria tend to be more and more codified to decide on the optimal treatment, however, there is no consensus.

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