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Management and outcome of cutaneous diphtheria in adolescent refugees in Germany, June 2022 - October 2023.
Infection
August 2024
Division for Paediatric Infectious Diseases and Rheumatology, Department of Paediatrics and Adolescent Medicine, University Medical Centre, Medical Faculty, University of Freiburg, Freiburg, Germany.
Article Synopsis
- There has been a rise in cutaneous infections caused by Corynebacterium diphtheriae among adolescent and young adult refugees in Germany since September 2022, prompting this study to assess treatment options and outcomes.
- The study included 31 cases from 9 medical centers, revealing that most infections were cutaneous and generally afebrile, with a few cases showing systemic complications requiring more intensive care.
- The recommended treatment for uncomplicated cases involves topical antiseptics and a 7-day course of antibiotics like clindamycin, while cases with fever or throat symptoms necessitate further medical evaluation, including cultures.
Diphtheria case detection and carrier study of close contacts: A step towards diphtheria eradication.
Indian J Pathol Microbiol
April 2024
Department of Microbiology, Bharati Vidyapeeth (Deemed to be University), Medical College and Hospital, Sangli, Maharashtra, India.
Introduction: Diphtheria is an infectious disease caused by gram-positive bacilli C. diphtheriae involving nasal, pharyngeal, tonsillar, or laryngeal mucus membranes. The mortality rate is as high as 20%, with India contributing almost 78% of the world incidence.
View Article and Find Full Text PDFLateral flow immunoassay-based laboratory algorithm for rapid diagnosis of diphtheria.
Open Res Eur
April 2023
Public Health Microbiology, National Conciliary Laboratory on Diphtheria, Bavarian Health and Food Safety Authority, Oberschleißheim, 85764, Germany.
In industrialised countries diphtheria is a rare but still life-threatening disease with a recent increase in cases due to migration and zoonotic aspects. Due to the rarity of the disease, laboratory diagnosis of diphtheria is often carried out in central reference laboratories and involves the use of sophisticated equipment and specially trained personnel. The result of the diphtheria agent detection can usually be obtained after 5-6 days or more.
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