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Developing an effective vaccine for haemorrhagic septicaemia (HS) in cattle and buffaloes is urgently needed. While preferred for their safety, achieving sufficient, cross-protective, and long-lasting immunity is still challenging when administering inactivated vaccines. This study aimed to assess the efficacy of four inactivating components comprising three inactivating agents: (1) Binary ethylenimine (BEI), (2) Formalin, (3) a combination of BEI and Formalin, and (4) Hydrogen peroxide (HO), in inactivating Pasteurella multocida to enhance HS vaccine potency.

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Background And Aim: Foot and mouth disease (FMD) is highly contagious in cloven-hoofed animals, and it causes outbreaks in Indonesia and several countries worldwide. This disease is caused by the FMD virus (FMDV), which belongs to the genus Aphthovirus and family Picornaviridae. In 1990, the World Organization for Animal Health Office International des Epizooties recognized Indonesia as an FMD-free country.

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Background And Aim: Leptospirosis is an infectious zoonotic disease that significantly affects animal health, particularly the reproduction of ruminants. However, some aspects of epidemiology and clinical characteristics have not been clarified. This study aimed to estimate the prevalence and identify risk factors of leptospirosis in female bovines at reproductive age in the Ecuadorian Amazon rainforest.

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Bovine adenovirus prevalence and its role in bovine respiratory disease complex: a systematic review and meta-analysis.

Vet J

January 2025

Davies Livestock Research Centre, School of Animal & Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, Australia; Australian Centre for Antimicrobial Resistance Ecology, School of Animal & Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, Australia. Electronic address:

Bovine adenoviruses (BAdVs) are major contributors to the bovine respiratory disease complex (BRDC). A systematic review and meta-analysis were carried out to explore the epidemiology of BAdV across diverse cattle populations using different detection methods. The study showed a higher BAdV prevalence of 0.

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Surveillance and genetic diversity of bovine viral diarrhea virus in dairy herds across Taiwan.

Vet J

January 2025

Graduate Institute of Microbiology and Public Health, National Chung Hsing University, Taichung 40227, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung 40227, Taiwan. Electronic address:

Bovine viral diarrhea virus (BVDV) significantly impacts cattle worldwide, causing respiratory, gastrointestinal, and reproductive disorders that lead to substantial economic losses. Despite its high global prevalence and various genotypes, the infection status of BVDV in Taiwan has not been reported. This study conducted large-scale surveillance in 2014, analyzing 460 bovine serum samples collected from 49 dairy herds across Taiwan.

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