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Article Synopsis
- Granuloma annulare is a noninfectious skin condition that appears as red or skin-colored plaques and can be difficult to diagnose due to its varied appearance, requiring correlation between clinical and histological findings.
- A case involving a 56-year-old woman who developed rashes after a tuberculin skin test is presented, with biopsy confirming granuloma annulare; treatment with topical and oral medications led to resolution of her symptoms.
- The exact cause of granuloma annulare remains unclear, with various potential triggers like trauma, infections, and immunizations; while it has different forms and mimics other skin diseases, it is generally a benign and self-limited condition.
The role of fiberoptic bronchoscopy in the management of perinatal tuberculosis: a case report.
J Matern Fetal Neonatal Med
December 2023
Department of Neonatology, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China.
Perinatal tuberculosis is a rare disease with high mortality and a challenging diagnosis. We reported a 56-day-old female infant with cough and wheezing. Her mother had miliary tuberculosis.
View Article and Find Full Text PDFApplication of transdermal patches with new skin test reagents for detection of latent tuberculosis.
J Med Microbiol
September 2019
Department of Research and Development, Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok 10330, Thailand.
Current intradermal tuberculin skin tests for latent tuberculosis infection (LTBI) based on purified protein derivative (PPD) have poor specificity. Developing a better skin test antigen as well as a simple skin patch test may improve and facilitate diagnostic performance. Defined recombinant antigens that were unique to (MTB), including two potential latency-associated antigens (ESAT-6 and Rv2653c) and five DosR-encoded latency proteins (Rv1996, Rv2031c, Rv2032, DevR and Rv3716c), were used as diagnostic skin test reagents in comparison with a standard PPD.
View Article and Find Full Text PDFSkin test of tuberculin purified protein derivatives with a dissolving microneedle-array patch.
Drug Deliv Transl Res
August 2019
State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, 368 Youyi Road, Wuhan, 430062, China.
Background: The tuberculin skin test (TST) is a long-established screening method for tuberculosis. However, the Mantoux technique is often difficult to reliably perform, which affects testing results and safety, which causes local skin pain and pruritus.
Methods: In this study, dissolving microneedle-array patches (MNP) were used to deliver purified protein derivative (PPD) tuberculin into the skin.
Steroid treatment in ocular tuberculosis: A double-edged sword?
J Fr Ophtalmol
February 2017
Service d'ophtalmologie, CHU de Pointe-à-Pitre-Abymes, route de Chauvel, 97159 Pointe-à-Pitre cedex, Guadeloupe.
Introduction: We report the case of a Caribbean patient with an atypical presentation of bilateral tuberculous chorioretinopathy.
Patient And Methods: A 57-year-old woman, with hypertension and non-insulin dependent diabetes, was referred to our center for a sudden loss of vision in the right eye to hand motions. Ophthalmic examination revealed only right papilledema.
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