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Successful staged surgery for advanced esophageal cancer after conversion pancreatoduodenectomy with pancreaticogastrostomy.
Clin J Gastroenterol
January 2025
Department of Gastroenterological Surgery and Pediatric Surgery, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu City, Gifu Prefecture, 501-1194, Japan.
Background: Complex surgery during initial cancer treatment can limit surgical options when planning management of a secondary malignancy. Subtotal esophagectomy and pancreatoduodenectomy are the most invasive and difficult procedures in gastroenterological surgery. Surgical cases in which subtotal esophagectomy was performed after pancreatoduodenectomy with pancreaticogastrostomy are extremely rare and challenging procedures due to the resulting complicated anatomical changes.
View Article and Find Full Text PDFGastric conduit in patients with previous endoscopic resection of the stomach for esophageal squamous cell carcinoma.
Dis Esophagus
January 2025
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
This study investigated the clinical outcomes of gastric conduits for esophageal reconstruction in esophageal squamous cell carcinoma (ESCC) patients who had previously undergone endoscopic resection of the stomach. From January 2006 to April 2023, a total of 1964 patients underwent surgery for esophageal cancer at our institution. After initially excluding 125 of these cases due to a histology other than ESCC, we identified 147 patients in the remaining population who had previously undergone a gastric endoscopic resection, among which 56 patients (67.
View Article and Find Full Text PDFObjective: To investigate the time delay effect from initial diagnosis to endoscopic submucosal dissection on superficial esophageal squamous cell carcinoma curability, considering the preoperative invasion depth.
Methods: This study included superficial esophageal squamous cell carcinoma diagnosed as T1a-epithelial/lamina propria mucosa cancer (cEP/LPM; cancer invading up to the lamina propria mucosa) or cT1a-muscularis mucosa (MM)/T1b-submucosal cancer (cMM/SM1; cancer invading up to 200 µm into the submucosa) and treated using endoscopic submucosal dissection from January 2017 to December 2021. We compared curability in lesions treated within three months (early treatment group) versus those treated ≥7 months post-diagnosis (delayed treatment group).
Endoscopic Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors.
Gut Liver
January 2025
Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Article Synopsis
- - The rise in superficial non-ampullary duodenal epithelial tumors (SNADETs) is linked to advancements in endoscopic imaging techniques and greater awareness of the condition.
- - Endoscopic resection is the primary treatment for SNADETs, utilizing various methods like cold snare polypectomy and underwater EMR, but poses more risks due to unique anatomical challenges in the duodenum.
- - Treatment strategies depend on the tumor size: smaller lesions may be treated with less invasive techniques, while larger or suspected cancerous tumors necessitate more aggressive approaches like endoscopic submucosal dissection or surgical resection.
Clinical significances of several fibrotic markers for prognosis in hepatocellular carcinoma patients who underwent hepatectomy.
Transl Cancer Res
May 2024
Department of Gastroenterology and Hepatology, University of Miyazaki Faculty of Medicine, Miyazaki, Japan.
Article Synopsis
- * Among 130 HCC patients who underwent surgery, it was found that severe fibrosis (cirrhosis) and specific markers like Type IV collagen 7S (T4C7) and Mac-2 binding protein glycosylation isomer (M2BPGi) are significantly associated with worse postoperative outcomes and tumor recurrence.
- * Key findings indicate that higher levels of T4C7 and M2BPGi, alongside advanced fibrosis stages, correlate with shorter cancer-free survival, suggesting that these fibrot
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