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| http://dx.doi.org/10.1136/adc.28.137.57 | DOI Listing |
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[Immunoglobulin A vasculitis].
Inn Med (Heidelb)
February 2024
Rheumatologie und Immunologie, Kantonsspital Aarau, Tellstraße 25, 5001, Aarau, Schweiz.
Article Synopsis
- Schoenlein-Henoch purpura is a type of immune-mediated small vessel vasculitis that is more common in children, often occurring after upper respiratory infections, while in adults, it presents more severely with a classic set of symptoms including skin, joint, and gastrointestinal issues, as well as kidney involvement.
- The underlying cause of this vasculitis is believed to be changes in the glycosylation of immunoglobulin A (IgA), leading to the formation of immune complexes that trigger inflammation and damage to blood vessels.
- Diagnosis typically involves detecting histological signs of vasculitis and may require kidney biopsies, and treatment focuses on managing symptoms and protecting kidney function, with a need for ongoing medical supervision due
Factors associated with surgical treatment in pediatric intussusception.
Wien Med Wochenschr
October 2022
Alimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background: The study aimed to identify factors related to the need for surgical treatment of intussusception in pediatric patients.
Methods: The medical charts of 106 patients diagnosed with intussusception and treated at the Imam Khomeini Medical Center in Ahvaz city between September 2019 and October 2020 were retrospectively reviewed. Patients were compared in terms of risk factor groups treated with surgery (12 pediatric patients) and nonsurgical methods (92 pediatric patients).
Serum Syndecan-1 levels in patients with immunoglobulin A vasculitis in children.
J Pediatr (Rio J)
September 2022
Gastrointestinal Lab, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang, China; Endoscopy center and Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang, China. Electronic address:
Objective: The aim of this study was to evaluate the serum Syndecan-1 (SDC-1) levels in patients with immunoglobulin-A vasculitis (IgAV) in children and its relation with gastrointestinal involvements.
Methods: Sixty-eight children with IgAV and 48 healthy children were enrolled in this cross-sectional study. Clinical and related laboratory data were collected from a computerized hospital database.
Henoch Schonlein purpura in pediatric patients with inflammatory bowel disease: A case series.
Pediatr Dermatol
September 2021
Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Retrospective chart review was conducted to identify the clinical features of Henoch Schonlein purpura (HSP) in five children with inflammatory bowel disease (IBD). All five children, four of which were on anti-TNF therapies, experienced the onset of HSP after their IBD diagnosis. HSP averaged 20.
View Article and Find Full Text PDFIntroduction to the special issue: "Focus on pediatric nephrology".
J Biol Regul Homeost Agents
November 2019
Chief UOSD Pediatric Nephrology, AOUP Policlinico G. Martino, Messina.
In this special issue, Researchers and Specialist Registrars of University of Catania, Catanzaro and Messina (ITALY) focused on nephron-urological abnormalities in children, ranging from glomerular (nephrosic and Alport syndrome, chronic glomerulonephritis) and urologic diseases (multicystic dysplastic kidney, obstructive pathologies and stones). Particular attention was paid to congenital syndrome, such as Vacterl, Fabry and Goldenhar syndrome and acquired conditions such as Schoenlein-Henoch disease potentially leading to renal impairment. In addition, oxidative stress in newborns is involved in the progression of renal failure.
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