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Green magnetically separable molluscicide Ba-Ce-Cu ferrite/TiO nanocomposite for controlling terrestrial gastropods Monacha Cartusiana.
Sci Rep
January 2025
Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, 36 Baochubei Road, Hangzhou, 310012, People's Republic of China.
The increasing economic damage caused by terrestrial gastropods, especially the Monacha cartusiana (M. cartusiana) land snail, to the agricultural sector requires a diligent and continuous search for new materials and alternatives for the control operations. In this piece of work, a magnetically separable molluscicide with high effectiveness green Barium-Cerium-Copper ferrite/TiO (Ba-Ce-CuFO/TiO) nanocomposite was greenly prepared using Eichhornia plant aqueous extract and characterized using different techniques.
View Article and Find Full Text PDFSymbiotic bacteria associated with entomopathogenic nematodes showed molluscicidal activity against Biomphalaria glabrata, an intermediate host of Schistosoma mansoni.
Parasit Vectors
December 2024
Department of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Background: Biomphalaria glabrata acts as the intermediate host of schistosomes that causes human schistosomiasis. Symbiotic bacteria, Xenorhabdus and Photorhabdus associated with Steinernema and Heterorhabditis, produce secondary metabolites with several biological activities. Controlling B.
View Article and Find Full Text PDFAssessment of molluscicidal activity of Syzygium aromaticum essential oil against Eobania vermiculata under laboratory and field conditions.
Toxicon
January 2025
Cell Biology, Histology and Genetics Division, Department of Zoology, Faculty of Science, Beni-Suef University, P.O. Box 62521, Beni-Suef, Egypt. Electronic address:
Article Synopsis
- The study assessed the toxic effects of clove oil on adult snails (Eobania vermiculata) due to their negative impact on agriculture.
- Exposure to sub-lethal concentrations of clove oil for one week resulted in significant biochemical changes in the snails, including alterations in enzyme levels and tissue disorganization.
- Although clove oil was less effective than the chemical methomyl in reducing snail populations, it remains a promising natural alternative for environmentally friendly pest control.
Exploring the impact of mitochondrial-targeting anthelmintic agents with GLUT1 inhibitor BAY-876 on breast cancer cell metabolism.
BMC Cancer
November 2024
Integrated Biosciences Graduate Program, University of Minnesota, 1035 Kirby Drive, Duluth, MN, 55812, USA.
Background: Cancer cells alter their metabolic phenotypes with nutritional change. Single agent approaches targeting mitochondrial metabolism in cancer have failed due to either dose limiting off target toxicities, or lack of significant efficacy in vivo. To mitigate these clinical challenges, we investigated the potential utility of repurposing FDA approved mitochondrial targeting anthelmintic agents, niclosamide, IMD-0354 and pyrvinium pamoate, to be combined with GLUT1 inhibitor BAY-876 to enhance the inhibitory capacity of the major metabolic phenotypes exhibited by tumors.
View Article and Find Full Text PDFNiclosamide attenuates calcification in human heart valvular interstitial cells through inhibition of the AMPK/mTOR signaling pathway.
Biochem Pharmacol
December 2024
College of Pharmacy, Mokpo National University, 1666 Yeongsan-Ro, Cheonggye-Myeon, Muan-Gun, Jeonnam 58554, Republic of Korea. Electronic address:
Calcific aortic valve disease (CAVD) is a considerable health burden with a lack of effective therapeutic options. There is an urgent need to develop interventions that inhibit the osteogenic transformation of valvular interstitial cells (VICs) and delay the calcification process. Niclosamide, an FDA-approved anti-helminthic drug, has emerged as a promising candidate that demonstrates a negative regulatory effect on porcine VICs calcification.
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