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There is paucity of studies focused on the enablers and barriers to community pharmacists' readiness to deprescribe inappropriate medications for older adults in developing settings. The current study assessed the enablers and barriers to community pharmacists' readiness to implement deprescribing of inappropriate medications for older adults. A cross-sectional survey of 252 community pharmacists was conducted in Qatar with a pre-tested 24-item questionnaire developed with the theory of domain framework.

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Novel genetic insight for psoriasis: integrative genome-wide analyses in 863 080 individuals and proteome-wide Mendelian randomization.

Brief Bioinform

November 2024

Department of Dermatology, Daping Hospital, Army Medical University, No. 10, Changjiang Branch Road, Yuzhong District, Chongqing 400042, China.

Psoriasis affects a significant proportion of the worldwide population and causes an extremely heavy psychological and physical burden. The existing therapeutic schemes have many deficiencies such as limited efficacies and various side effects. Therefore, novel ways of treating psoriasis are urgently needed.

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Pre-exposure prophylaxis (PrEP) has proven to be a powerful tool in preventing HIV infection. There is limited information about the factors associated with willingness to use different PrEP modalities among adolescent girls and young women (AGYW) in Africa. We assessed willingness to use long-acting injectable PrEP (LAI-PrEP) among 14-24-year-old AGYW at high risk of HIV in Uganda, and associated factors determined using multivariable complementary log-log regression.

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Assessing blood metal levels in house sparrows (Passer domesticus) across urban and rural habitats in Meknes.

Environ Sci Pollut Res Int

January 2025

Natural Resources Management and Development Team, Environment and Health Laboratory, Department of Biology, Faculty of Sciences, Moulay Ismaïl University, Zitoune, B.P.11201, Meknes, Morocco.

This study investigates the concentration of heavy metals lead (Pb), cadmium (Cd), and zinc (Zn) in the blood of house sparrows (Passer domesticus) across various urban habitats in Meknes, Morocco. Fifty adult sparrows were captured from five distinct sites, including industrial, high-traffic, and rural areas. Blood samples were specifically analyzed for Pb, Cd, and Zn using Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES).

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Groove pancreatitis (GP) is a chronic segmental pancreatitis which leads to altered pancreatic secretions and pancreatitis. The exact pathogenesis of GP has not been clearly identified to date but heavy smoking and chronic alcohol consumption seem to be the main factors involved. The resulting chronic pancreatitis (CP) is a debilitating disease causing abdominal pain often refractory to medical therapy, so much that the main indication for surgical treatment is intractable abdominal pain.

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