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Cornea
March 2025
Department of Ophthalmology, Unidade Local de Saúde de São João, Porto, Portugal.
Purpose: Maroteaux-Lamy syndrome (MPSVI) is a rare lysosomal storage disorder caused by an Arylsulfatase B (ARSB) deficiency, leading to dermatan sulfate and chondroitin-4-sulfate accumulation. It manifests various systemic clinical features. Enzyme Replacement Therapy with Galsulfase (Naglazyme) manages systemic symptoms, but ocular manifestations, such as corneal opacity, often require surgery.
View Article and Find Full Text PDFToxicol Pathol
March 2025
UConn School of Medicine, Department of Anatomic Pathology and Laboratory Medicine, Farmington, Connecticut, USA.
Two dark and raised foci were observed on the left hemisphere of the brain of a 3-year-old cynomolgus monkey during the routine necropsy procedures of a preclinical toxicity study. Microscopic examination revealed a lesion in the cerebral cortex at the junction of the parietal and occipital lobes, consisting of disorganized, but generally well-circumscribed collections of mixed glial and neuronal cells within a fibrillar stroma. Numerous eosinophilic granular bodies, brown pigment-laden macrophages, and lymphocytic infiltrates were also noted.
View Article and Find Full Text PDFAnimals (Basel)
March 2025
Department of Biology and Marine Biology, College of Science and Engineering, University of North Carolina Wilmington, Wilmington, NC 28403, USA.
The glymphatic system, an analog of the peripheral lymphatic system in the brain, and the meningeal lymphatic system are critical to central nervous system health. The glymphatic system functions to distribute cerebrospinal fluid and important compounds throughout the brain and to remove metabolic waste. The flow of cerebrospinal fluid through this system is affected by changes in cerebral blood flow, intracranial pressure, and vascular tone.
View Article and Find Full Text PDFAnimals (Basel)
February 2025
Department of Comparative Biomedicine and Food Science (BCA), University of Padova, Viale dell'Università, 16, 35020 Legnaro, PD, Italy.
Reducing the environmental impact of poultry farming aligns with the European Green Deal's goal of climate neutrality and sustainable food production. Local chicken breeds and low-input diets are promising strategies to achieve this goal. This study evaluated the effects of diet (standard vs.
View Article and Find Full Text PDFPol Merkur Lekarski
March 2025
Kharkiv National Medical University, Kharkiv, Ukraine.
Objective: Aim: The purpose was to determine the morphological features of collagen fibers of the dermis and regenerate filling the cavity of the experimental skin wound during its closure by different methods..
Patients And Methods: Materials and Methods: The experimental study was conducted on 60 rats of the WAG population weighing 250-300 grams.
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