Anticarcinogenic effects of the fumaric acid was studied in two rat models of carcinogenesis. Tumors of the esophagus, forestomach, tongue and throat were induced by peroral instillation of 35 mg/kg body weight N-methyl-N-benzylnitrosamine, and neurogenic and renal ones--by transplacental injection of 75 mg/kg body weight N-ethyl-N-nitrosourea. The fumaric acid given in drinking water in the dose of 1 g/l at the postinitiation stage of the carcinogenesis was shown to inhibit the development of esophageal papilloma, brain glioma and mesenchymal tumors of the kidney.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
reconstructed prism-like CuO on copper foam assisted by fumaric acid for an enhanced electrochemical nitrate reduction reaction.
Dalton Trans
January 2025
Sun Yat-Sen University, MOE Laboratory of Polymeric Composite and Functional Materials, School of Materials Science and Engineering, Guangzhou 510275, China.
The electrochemical nitrate reduction reaction (NORR) is considered as a promising strategy for addressing environmental pollution and sustainable energy development. In this study, prism-like CuO loaded on copper foam (CuO/CF) was synthesized in a simple solvothermal reaction and an electrochemical reconstruction process. The electrochemical reconstruction process facilitates the formation of a CuO lattice structure on copper foam derived from FU-CF generated by the reaction of copper foam and fumaric acid (HFU) in DMF.
View Article and Find Full Text PDFTrade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostases.
Plants (Basel)
January 2025
Department of Turf Science and Engineering, College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
White clover () is an excellent perennial cold-season ground-cover plant for municipal landscaping and urban greening. It is, therefore, widely distributed and utilized throughout the world. However, poor salt tolerance greatly limits its promotion and application.
View Article and Find Full Text PDFInvestigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis.
Animals (Basel)
January 2025
Institute of Animal Husbandry and Veterinary Science, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China.
Asthma has been extensively studied in humans and animals, but the molecular mechanisms underlying asthma in Meishan pigs, a breed with distinct genetic and physiological characteristics, remain elusive. Understanding these mechanisms could provide insights into veterinary medicine and human asthma research. We investigated asthma pathogenesis in Meishan pigs through transcriptomic and metabolomic analyses of blood samples taken during autumn and winter.
View Article and Find Full Text PDFCurrent Perspectives in Detection of Bioactive Compounds From Through GC-MS and LC-MS/MS: Antioxidant Properties and In Silico Analysis for Industrial Applications.
Biochem Res Int
January 2025
Department of Animal Nutrition, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Members of the genus are the conventional medicinal plants used in the therapeutic management of numerous ailments, especially for their antioxidant and pharmacological activities. The crude extract of was profiled using high-resolution GC-MS and LC-MS/MS techniques to determine possible bioactive compounds that are vital to the antioxidant activity. A total of 52 and 63 bioactive compounds have been detected in GC-MS chromatograms using different solvents (methanol and ethanol) in leaf extracts, representing the presence of certain bioactive compounds.
View Article and Find Full Text PDFComparative analysis of LC-HRMS profiling, ATR FT-IR spectroscopy, antioxidant, anti-diabetic, and anti-tyrosinase activities of extracts from Cotoneaster frigidus Wall. Ex Lindl. "Cornubia" fruit.
Food Res Int
February 2025
Karadeniz Technical University, Faculty of Science, Department of Chemistry, Trabzon, Türkiye. Electronic address:
The antioxidant, total phenolic, flavonoid, and anthocyanidin properties of extracts prepared from Cotoneaster frigidus Wall. ex Lindl. "Cornubia" fruit were examined.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!