Bioptates and resected material from patients treated for cancer of the esophagus at the Kazakh Research Institute of Oncology in 1980-1989 were analysed. Adenogenic tumors made up 6.0% of the 1671 cases of esophageal cancer studied. A gradual increase in the percentage of adenogenic cancers was established (P < 0.05). A group of 100 cases of adenogenic cancers was examined in detail. Adenocarcinoma made up 5.3%, adenosquamous cancer--0.5 and adenocystic cancer--0.2%. Adenogenic cancers most often occurred in the lower thoracic part of the organ. Poorly differentiated adenocarcinoma predominated (56.8%), with a tendency to an increase in the tumor occurrence in the upper and mid-thoracic parts. The enhanced morbidity from adenogenic cancers is attributed to a high occurrence of esophagitis in the majority of regions of Kazakhstan.
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