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Treatment of facial reactive B-cell rich lymphoid proliferation with dapsone.
J Dermatol
January 2025
Department of Dermatology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Reactive B-cell rich lymphoid proliferation (rB-LP), once called pseudolymphoma, is a benign lymphoproliferative disorder, which is histologically characterized by dense dermal infiltrate forming reactive germinal centers with tingible body macrophages. The disease frequently involves the face, scalp, and ear lobes. Treatment includes topical or intralesional steroids, surgical resection, ultraviolet therapy, laser treatment, and radiation therapy.
View Article and Find Full Text PDF[Effect of "Zhibian" (BL54)-toward-"Shuidao" (ST28) acupuncture on reproductive function in mice with asthenozoospermia based on mitochondrial apoptosis].
Zhongguo Zhen Jiu
January 2025
College of Acupuncture-Moxibustion and Tuina, Chengdu University of TCM, Chengdu 610075, Sichuan Province, China; Second Clinical College, Shanxi University of CM, Jinzhong 030619.
Objective: To observe the effects of the "Zhibian" (BL54)-toward-"Shuidao" (ST28) acupuncture on key regulatory factors during mitochondrial apoptosis of testicular tissue in asthenozoospermia mice, and explore the potential mechanism of the protective effect of acupuncture on reproductive function.
Methods: Thirty C57BL/6 male mice were randomly divided into a blank group, a model group and an acupuncture group, 10 mice in each group. In the model and the acupuncture groups, the intraperitoneal injection of cyclophosphamide (30 mg•kg•d) was delivered for 7 days to prepare the asthenozoospermia model.
Case report of disseminated borrelial lymphocytoma with isolation of sensu stricto in chronic lymphatic leukemia stage Binet A-an 11 year follow up.
Front Med (Lausanne)
October 2024
National Reference Center for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany.
Article Synopsis
- The case report describes a patient with chronic lymphocytic B cell leukemia (B-CLL) who developed skin lesions that were initially misdiagnosed as leukemia cutis but were later identified as cutaneous borreliosis (specifically lymphocytoma).
- Borrelia bacteria were successfully isolated from the patient’s skin lesions, and antibiotic treatment resulted in significant improvement, although a second course of antibiotics was necessary for full resolution.
- After 11 years of follow-up, the patient remained free of skin lesions and stable in her B-CLL condition without needing chemotherapy, highlighting the interplay between Lyme disease and pre-existing malignancies.
Article Synopsis
- Cutaneous reactive lymphoid proliferation (CRLP) mimics cutaneous lymphoma, making it essential to differentiate between the two for correct diagnosis and treatment.* -
- CRLP can be caused by factors like viruses, drugs, or skin trauma, and requires careful evaluation of clinical and histopathological features for accurate diagnosis.* -
- A case study highlighted CRLP linked to antidepressant and antihypertensive medications, where excision confirmed the diagnosis, showing benign characteristics with no clonality and prompting ongoing monitoring for recurrence.*
Skin Changes in Suspected Lyme Disease.
Acta Dermatovenerol Croat
December 2023
Pero Vržogić, MD, Naftalan Special Hospital for Medical Rehabilitation, Ivanić Grad, Croatia;
Article Synopsis
- Ticks are a significant health concern in Croatia and worldwide due to their role in transmitting various diseases, including Lyme borreliosis, which is caused by the Borrelia burgdorferi bacterium.
- In Croatia, the incidence rate of Lyme borreliosis is approximately 6.51 cases per 100,000 people, highlighting the risk of infection from ticks.
- The article describes a case of a 58-year-old woman with Lyme disease who had skin manifestations that fully regressed after successful treatment, demonstrating the importance of early diagnosis and intervention.
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