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GOLD grade-specific characterization of COPD in the COSYCONET multi-center trial: comparison of semiquantitative MRI and quantitative CT.
Eur Radiol
January 2025
Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.
Objectives: We hypothesized that semiquantitative visual scoring of lung MRI is suitable for GOLD-grade specific characterization of parenchymal and airway disease in COPD and that MRI scores correlate with quantitative CT (QCT) and pulmonary function test (PFT) parameters.
Methods: Five hundred ninety-eight subjects from the COSYCONET study (median age = 67 (60-72)) at risk for COPD or with GOLD1-4 underwent PFT, same-day paired inspiratory/expiratory CT, and structural and contrast-enhanced MRI. QCT assessed total lung volume (TLV), emphysema, and air trapping by parametric response mapping (PRM, PRM) and airway disease by wall percentage (WP).
Low-Dose Whole-Chest Dynamic CT for the Assessment of Large Airway Collapsibility in Patients with Suspected Tracheobronchial Instability.
Radiol Cardiothorac Imaging
October 2024
From the Department of Diagnostic and Interventional Radiology, Translational Lung Research Center (TLRC), Subdivision of Pulmonary Imaging, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany (A.B., O.W., R.R., H.U.K., C.P.H., M.O.W.); Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany (A.B., O.W., R.R., H.U.K., F.T., C.P.H., F.J.F.H., M.O.W.); Department of Diagnostic and Interventional Radiology with Nuclear Medicine (A.B., O.W., R.R., H.U.K., C.P.H., M.O.W.) and Department of Pulmonary Medicine (F.T., F.J.F.H.), Thoraxklinik at the University Hospital of Heidelberg, Heidelberg, Germany; Department of Radiology, Division of Pediatric Radiology, Medical University of Graz, Graz, Austria (A.D.); Department of Internal Medicine II, Division of Pulmonology, Medical University of Vienna, Vienna, Austria (D.G.); Department of Pneumology and Critical Care Medicine, Asklepios Klinik Barmbek, Hamburg, Germany (R.E.); and Institute of Medical Informatics, University of Lübeck, Lübeck, Germany (M.H., F.F.).
Article Synopsis
- - The study aimed to evaluate tracheal collapsibility using low-dose 4D CT, comparing the results with traditional methods like inspiratory-expiratory CT and bronchoscopy in patients suspected of tracheal collapse.
- - Researchers analyzed 4D CT scans from 52 patients, finding that 48% exhibited significant tracheal collapsibility (50% or greater) and noted differences between visual 4D CT assessments and other diagnostic methods regarding detection rates of collapsibility.
- - Results showed that 4D CT was superior in identifying patients with severe collapsibility compared to both paired CT and bronchoscopy, with significant differences in collapsibility measurements between the groups assessed.
Clinically Relevant Extracardiac Findings at Cardiac Imaging: Insights from the European MR/CT Registry.
Radiol Cardiothorac Imaging
October 2024
From Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland (L.J.M., M.E., H.A.); Department of Diagnostic and Interventional Radiology, Herzzentrum Leipzig Universitatsklinik, Leipzig, Germany (M.G., R.F.G., C. Lücke); Department of Radiology, University Medical Center Groningen, Groningen, the Netherlands (R.V.); Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Humanitas Research Hospital, Rozzano, Italy (M.F.); IRCCS Humanitas Research Hospital, Milan, Italy (M.F.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (R.P.J.B.); Department of Radiology, Antwerp University Hospital and Antwerp University, Antwerp, Belgium (R.S.); Department of Diagnostic and Interventional Radiology, University Hospital Centre Zagreb, Zagreb, Croatia (M.H.P.); Department of Radiology, University Medical Centre Maribor, Maribor, Slovenia (M.P.); Department of Biomedical Imaging and Image-Guided Therapy, Division of Cardiovascular and Interventional Radiology, Medical University of Vienna, Vienna, Austria (C. Loewe); Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany (K.N.); British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom (M.C.W.); School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (G.M.); Department of Radiology, IRCCS Istituto Auxologico Italiano, San Luca Hospital, Milan, Italy (G.M.); and Department of Radiological Sciences-Institute of Radiology, Catholic University of Rome, A. Gemelli University Hospital, Rome, Italy (L.N.).
Article Synopsis
- The study aimed to assess how often clinically relevant extracardiac findings occur during cardiac CT and MRI exams across various patient demographics and examination reasons.
- The analysis included over 200,000 cardiac CT scans and over 228,000 cardiac MRI scans, revealing extracardiac findings in 3.28% of CT exams and 1.50% of MRI exams, with higher rates associated with specific procedures like transcatheter aortic valve replacement.
- Older patients showed a significant increase in the prevalence of these findings, emphasizing the importance of age and examination purpose in assessing patient outcomes.
Nationwide Survey - What is important for a sustainable radiology?
Rofo
September 2024
Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Radiology departments with the large diagnostic devices CT and MRI contribute significantly to the overall energy consumption of health facilities. However, there is a lack of systematic knowledge about the opinions of radiological staff on the most relevant aspects of sustainability. For this reason, we conducted a comprehensive survey for radiology employees on sentiment and experiences regarding sustainability in radiology.
View Article and Find Full Text PDFReproducibility and Repeatability of US Shear-Wave and Transient Elastography in Nonalcoholic Fatty Liver Disease.
Radiology
September 2024
From the Center for Ultrasound Research and Translation, Massachusetts General Hospital, 55 Fruit St, White Bldg, Rm 270, Boston, MA 02114 (T.T.P., A.O., X.W., Q.L., D.H., M.M., H.E., A.E.S.); Harvard Medical School, Boston, Mass (T.T.P., A.O., Q.L., A.E.S.); Pfizer, Cambridge, Mass (S.P.S.); Department of Radiology, University of Washington, Seattle, Wash (G.M.C.); Department of Ultrasound, Shenzhen University General Hospital, Shenzhen, China (Q.L.); Department of Radiology, Liver Imaging Group, University of California San Diego, La Jolla, Calif (M.S.M., Y.C., C.B.S., K.J.F.); MGH Fatty Liver Program, Gastrointestinal Unit, Massachusetts General Hospital, Boston, Mass (K.E.C.); BioAge Labs, Richmond, Calif (S.S.S.); Foundation for the National Institutes of Health, North Bethesda, Md (H.H., T.N.K.); Regeneron Pharmaceuticals, Tarrytown, NY (R.A.C.); Department of Medicine, Division of Gastroenterology, NAFLD Research Center, University of California at San Diego, La Jolla, Calif (R.L.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Department of Internal Medicine, Division of Internal Medicine, Division of Gastroenterology, Virginia Commonwealth University Medical Center, Richmond, Va (A.J.S.).
Background US shear-wave elastography (SWE) and vibration-controlled transient elastography (VCTE) enable assessment of liver stiffness, an indicator of fibrosis severity. However, limited reproducibility data restrict their use in clinical trials. Purpose To estimate SWE and VCTE measurement variability in nonalcoholic fatty liver disease (NAFLD) within and across systems to support clinical trial diagnostic enrichment and clinical interpretation of longitudinal liver stiffness.
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