Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Resveratrol mitigates heat stress-induced testicular injury in rats: enhancing male fertility via antioxidant, antiapoptotic, pro-proliferative, and anti-inflammatory mechanisms.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, 22758, Egypt.
This study investigates the protective effects of resveratrol (RSV) against heat stress (HS)-induced testicular injury in rats. Climate change has exacerbated heat stress, particularly affecting male fertility by impairing testicular function and sexual behavior. A total of 32 rats were allocated into four experimental groups: control, RSV control, HS control, and RSV + HS.
View Article and Find Full Text PDFPhotobiomodulation Improves Histological Parameters of Testis and Spermatogenesis in Adult Mice Exposed to Scrotal Hyperthermia in the Prepubertal Phase.
J Lasers Med Sci
September 2024
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study investigates how photobiomodulation (PBM) affects the testis of prepubertal male mice exposed to heat stress, which is known to damage testicular health.
- Twenty-four male mice were divided into three groups: a control group, a hyperthermia group, and a hyperthermia plus PBM group, where heat was applied to induce stress and laser therapy was used to assess its protective effects.
- Results showed that the PBM treatment improved sperm quality, increased testicular cell counts, boosted testosterone levels, and reduced harmful oxidative stress, suggesting that laser therapy can help protect the testis from heat damage during critical developmental periods.
Protective impact of Betanin against noise and scrotal hyperthermia on testicular toxicity in Wistar rat: Role of apoptosis, oxidative stress and inflammation.
Heliyon
October 2024
Zanjan Applied Pharmacology Research Center, Health and Metabolic Diseases Research Institute, Zanjan University of Medical Sciences, Zanjan, Iran.
Article Synopsis
- Heat exposure and white noise can harm reproductive organs, so this study looks at whether betanin can reduce these negative effects in rodent testicular tissue.
- Wistar rats were split into six groups to test different conditions including control, betanin treatment, noise exposure, and hyperthermia, with specific methodologies for inducing heat and noise stress.
- Results showed that betanin effectively reduced oxidative damage, apoptosis, and inflammation in the rats' testicular tissues, indicating its protective benefits against acute testicular toxicity caused by heat and noise exposure.
The Impact of Photobiomodulation Therapy on Enhancing Spermatogenesis and Blood-Testis Barrier Integrity in Adult Male Mice Subjected to Scrotal Hyperthermia.
J Lasers Med Sci
September 2024
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- Unhealthy lifestyle choices like alcohol, chemicals, and heat stress can negatively impact male fertility by damaging the blood-testis barrier (BTB), which is crucial for sperm production.
- Recent studies have explored photobiomodulation therapy (PBMT) as a way to improve sperm quality, particularly in cases with genital inflammation.
- In an experiment with male mice subjected to heat stress, PBMT was found to significantly enhance sperm quality and the health of the BTB, offering a promising method for treating male infertility.
The effects of vitamin C and vitamin B12 on improving spermatogenesis in mice subjected to long-term scrotal heat stress.
Clin Exp Reprod Med
December 2024
Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- Scrotal hyperthermia negatively affects sperm production and male fertility, prompting this study to explore the impact of vitamins B12 and C in adult male mice exposed to prolonged heat.
- After 35 days of vitamin treatment, vitamin C showed greater improvements in sperm quality and reduced cell death compared to vitamin B12, alongside beneficial changes in oxidative stress markers.
- The study concludes that vitamins B12 and C may offer therapeutic benefits for male reproductive health under heat stress, suggesting vitamin supplementation as a viable strategy to combat fertility issues linked to increased scrotal temperatures.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!