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Current status of drug therapy for chronic hepatitis B.

World J Gastroenterol

January 2025

Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

In this editorial, we comment on the article by Meng . Chronic hepatitis B (CHB) is a significant global health problem, particularly in developing countries. Hepatitis B virus (HBV) infection is one of the most important risk factors for cirrhosis and hepatocellular carcinoma.

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In this article, we comment on an article published in a recent issue of the . We specifically focus on the roles of human leukocyte antigen (HLA) and donor-specific antibodies (DSAs) in pediatric liver transplantation (LT), as well as the relationship between immune rejection after LT and DSA. Currently, LT remains the standard of care for pediatric patients with end-stage liver disease or severe acute liver failure.

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Neuroimmune axis: Linking environmental factors to pancreatic β-cell dysfunction in Diabetes.

Brain Behav Immun Health

February 2025

Laboratory of Immuno-Endocrinology, Diabetes and Metabolism, Instituto de Investigaciones en Medicina Traslacional (IIMT), CONICET-Universidad Austral, Pilar, Argentina.

Pancreatic β-cells are specialized in secreting insulin in response to circulating nutrients, mainly glucose. Diabetes is one of the most prevalent endocrine-metabolic diseases characterized by an imbalance in glucose homeostasis, which result mainly from lack of insulin production (type 1 diabetes) or insufficient insulin and peripheral insulin resistance (type 2 diabetes), both influenced by genetic and environmental components. Pancreatic β-cell dysfunction and islet inflammation are common characteristics of both types of the disease.

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I had a dream.

J Cell Commun Signal

March 2025

International CCN Society Nice France.

Expressing hopes and desires is an essential part of communication, and communication is the major pillar of the Journal of Cell Communication and Signaling. There comes the time of giving the responsibility of leading JCCS to a new editor in chief and I am taking this opportunity to comment on a few recent milestones and future of the journal which I created in 2007, after I had created "Cell Communication and Signaling" 20 years ago (1), one of the first open access journals.

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Article Synopsis
  • The creation of sustainable food systems is complex and involves various interconnected issues, making it a "wicked problem."
  • There is no single solution that applies universally; different approaches may be needed based on local contexts and challenges.
  • Addressing this issue requires collaboration among diverse stakeholders to foster innovative and adaptable strategies.
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