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Reliability of 4D Flow MRI for Investigation of Fetal Cardiovascular Hemodynamics in the Third Trimester.

Radiol Cardiothorac Imaging

December 2024

From the Departments of Radiology (E.K.E., T.F., M.L.M., L.P.B., A.J.B.), Pediatrics-Cardiology (R.M.F.), and Bioengineering (A.J.B.), University of Colorado Anschutz Medical Campus, 13123 E 16th Ave B125, Aurora, CO 80045; and Department of Radiology, Children's Hospital Colorado, Aurora, Colo (S.A.S., A.J.B.).

Article Synopsis
  • The study aimed to establish reference values for fetal 4D flow MRI and assess its reliability in measuring blood flow in healthy fetuses and those with suspected aortic coarctation (CoA).
  • Researchers conducted MRI scans on 34 pregnant patients, collecting data from both healthy fetuses and those with potential cardiovascular issues, analyzing the accuracy and consistency of the flow measurements obtained.
  • The results indicated that fetal 4D flow MRI provides reliable hemodynamic measurements with high precision and repeatability, although it tends to underestimate blood flow compared to traditional 2D phase contrast MRI techniques.
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Article Synopsis
  • The text discusses a rare case of a female patient with Turner syndrome (TS) who faced congenital pulmonary issues, including emphysema and pulmonary hypertension, developing over time.
  • The patient experienced significant health challenges from infancy through adulthood, including heart dysfunction, surgical interventions, and multiple medical treatments.
  • The study suggests that altered lymphatic drainage in utero may lead to lung abnormalities in TS patients, advocating for continuous monitoring and management of potential cardiopulmonary complications.
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Fetal cardiovascular magnetic resonance feature tracking myocardial strain analysis in congenital heart disease.

J Cardiovasc Magn Reson

December 2024

Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany; Quantitative Imaging Lab Bonn (QILaB), University Hospital Bonn, Bonn, Germany. Electronic address:

Article Synopsis
  • Cardiovascular magnetic resonance (CMR) is an advanced imaging technique used to evaluate the heart's anatomy and function in fetuses with congenital heart disease (CHD).
  • The study compared myocardial strain measurements (like global longitudinal strain) between healthy fetuses and those with various types of CHD using detailed imaging analysis.
  • Results showed significant differences in strain values for certain types of CHD, indicating that fetal CMR is effective for assessing heart function and could help in understanding the impact of different CHD subtypes.
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A 24-year-old man was referred to our tertiary care center for the management of uncontrolled hypertension secondary to severe coarctation of aorta.

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The introduction of surgical simulation on three-dimensional-printed models in the cardiac surgery curriculum: an experimental project.

J Cardiovasc Med (Hagerstown)

February 2024

Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua.

Aims: Training in congenital cardiac surgery has become more and more difficult because of the reduced opportunities for trainees in the operating room and the high patient anatomical variability. The aim of this study was to perform a pilot evaluation of surgical simulation on a simple 3D-printed heart model in training of young surgeons and its potential inclusion in the curriculum of residency programs.

Methods: A group of 11 residents performed a surgical correction of aortic coarctation using a 3D-printed surgical model.

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