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Portable Electrochemical System and Platform with Point-of-Care Determination of Urine Albumin-to-Creatinine Ratio to Evaluate Chronic Kidney Disease and Cardiorenal Syndrome.
Biosensors (Basel)
September 2024
Department of Industrial Design, National Cheng Kung University, Tainan 701401, Taiwan.
The urine albumin (Alb)-to-creatinine (Crn) ratio (UACR) is a sensitive and early indicator of chronic kidney disease (CKD) and cardiorenal syndrome. This study developed a portable and wireless electrochemical-sensing platform for the sensitive and accurate determination of UACR. The developed platform consists of a carbon nanotube (CNT)-2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)(ABTS)-based modified UACR sensor, a miniaturised potentiostat, a cup holder embedded with a magnetic stirrer and a smartphone app.
View Article and Find Full Text PDFTimolol Maleate Ophthalmic Mucoadhesive-Thermosensitive Gel: Development and Characterization.
Turk J Pharm Sci
September 2024
Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Türkiye.
Objectives: The aim of this study was to prepare a sustained-delivery mucoadhesive-thermosensitive formulation containing poloxamer 338 (P338), poloxamer 188 (P188), and mucoadhesive agents, such as chitosan (CHT) and carboxymethylcellulose (CMC), to increase the ophthalmic bioavailability of timolol maleate (TM).
Materials And Methods: Gels were prepared by mixing different amounts of P338, P188, and a mucoadhesive agent in cold isotonic water using a magnetic stirrer. The sol-gel gelation time of the gels was determined using the test tube inversion method.
Design and characterization of a low-cost particle image velocimetry system.
HardwareX
September 2024
Department of Engineering, Ashesi University, 1 University Ave, Berekuso, Ghana.
Particle Image Velocimetry (PIV) is considered the gold standard technique for flow visualization. However, its cost (at least tens of thousands of dollars) can prove inhibitive in its standard form. This article presents an alternative design, leveraging off-the-shelf and open-source options for each key component involved: camera, laser module, optical components, tracer particles, and analysis software.
View Article and Find Full Text PDFA Comparative Study on the Antidiabetic Activity, Cytotoxicity and Lipid Profile of Oils.
Plants (Basel)
August 2024
Department of Natural Products, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
The plant is traditionally used for medicinal and food purposes. However, there are limited studies on the bioactivity and cytotoxicity of its seed butter and aril oil. This study aimed to assess the antidiabetic activity and cytotoxicity of seed butter and aril oil, obtained via two different extraction methods, and compare their lipid profiles.
View Article and Find Full Text PDFLaser-Assisted Preparation of TiO/Carbon/Ag Nanocomposite for Degradation of Organic Pollutants.
Materials (Basel)
August 2024
Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
The ever-increasing expansion of chemical industries produces a variety of common pollutants, including colors, which become a global and environmental problem. Using a nanocatalyst is one of the effective ways to reduce these organic contaminants. With this in mind, a straightforward and effective method for the production of a novel nanocatalyst based on lignin-derived carbon, titanium dioxide nanoparticles, and Ag particles (TiO/C/Ag) is described.
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