Objectives: To assess the diagnostic value of prenatal magnetic resonance imaging (MRI) in addition to prenatal ultrasound in a case of fetal varicella syndrome.
Methods: Comparison of prenatal ultrasound and MRI features obtained at 26 and 32 weeks, respectively, with neonatal imaging (ultrasound, MRI and CT) and macroscopic and microscopic pathology findings in a fatal case of varicella embryopathy.
Results: Prenatal ultrasound correlated fairly well with neonatal imaging and pathology findings. Most lesions of thoracic, abdominal and retroperitoneal viscera, limb involvement and even dermatologic features were apparent on ultrasonography. Involvement of the CNS, including cerebellar hypoplasia, was not apparent on ultrasound examination, but was clearly demonstrated by prenatal MRI.
Conclusion: If maternal seroconversion for the varicella-zoster virus is suspected, combining prenatal ultrasound and magnetic resonance imaging may document the extent of tissue damage in fetal varicella syndrome to a larger extent than has been reported until now and therefore contribute to due counselling following maternal varicella exposure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/pd.669 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Atypical mediastinal mass in the fetus: a review of the literature.
Arch Gynecol Obstet
January 2025
Department of Congenital Cardiac Surgery, IRCCS Policlinico San Donato, 20097, San Donato, Milan, Italy.
Objectives: Congenital thoracic masses (CTMs) are suspected in presence of solid or cystic thoracic lesions at ultrasound. The common typical fetal CTMs encompass: hyperechogenic lung lesions such as congenital pulmonary airway malformation (CPAM), broncopulmonary sequestration (PS) and congenital high airway obstruction syndrome (CHAOS); less common solid thoracic masses are mediastinal/pericardial tumors as rhabdomyoma and teratoma. The aim of our study is to gather the available evidence on cases of atypical CTMs of difficult classification, for which the diagnosis remains often uncertain.
View Article and Find Full Text PDFObjectives: This study aimed to assess the role of olfactory sulci (OS) in diagnosing CHARGE syndrome among fetuses with major congenital heart defects (CHDs).
Methods: We prospectively evaluated OS development in fetuses diagnosed with CHDs from 2017 to 2021. Neurosonography (NSG) was performed using transabdominal and transvaginal approaches after 30 weeks of gestation.
Congenital conjunctival cyst detected by prenatal ultrasound.
Am J Ophthalmol Case Rep
March 2025
University of South Carolina/Prisma Health, Columbia, SC, USA.
Purpose: The purpose of this manuscript is to report a rare case of an orbital cyst detected intrauterine with sonography.
Observation: A 23-year-old female presented for routine prenatal monitoring when an orbital cyst was detected with a transabdominal ultrasound. Uncomplicated cesarean section was performed at 38 weeks gestation with proptosis of the left globe being noted on ophthalmic examination of the newborn.
Sonographic Findings in Two Consecutive Pregnancies Affected with Fetuses of Congenital Nephrotic Syndrome of Finnish Type.
J Med Ultrasound
November 2024
Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, Guangdong, China.
Early Diagnosis of a Rare Genetic Syndrome by the First-trimester Ultrasound Combined with Exome Sequencing.
J Med Ultrasound
September 2024
Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou, Guangdong, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!