The diagnostic criteria used to identify developmental apraxia of speech (DAS) have been at the center of controversy for decades. Despite the difficulty in determining the characteristics that differentiate DAS from other speech acquisition disorders, many children are identified with this disorder. The current report presents the criteria used by 75 speech-language pathologists to establish a diagnosis of DAS. Although 50 different characteristics were identified, 6 of these characteristics accounted for 51.5% of the responses. These characteristics included inconsistent productions, general oral-motor difficulties, groping, inability to imitate sounds, increasing difficulty with increased utterance length, and poor sequencing of sounds. These results are consistent with the general ambiguity of the diagnostic criteria of DAS and suggest that no single deficit is used among clinicians.
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http://dx.doi.org/10.1044/1058-0360(2003/083) | DOI Listing |
JMIR Form Res
January 2025
Department of Medical Informatics, Amsterdam UMC - University of Amsterdam, Amsterdam, Netherlands.
Background: The prognosis for patients with several types of cancer has substantially improved following the introduction of immune checkpoint inhibitors, a novel type of immunotherapy. However, patients may experience symptoms both from the cancer itself and from the medication. A prototype of the eHealth tool Cancer Patients Better Life Experience (CAPABLE) was developed to facilitate symptom management, aimed at patients with melanoma and renal cell carcinoma treated with immunotherapy.
View Article and Find Full Text PDFMedwave
January 2025
Departamento de Cirugía, Hospital Clínico de la Universidad de Chile, Chile.
Introduction: Lung cancer is the leading cause of death by cancer worldwide and has a high lethality. The best treatment for patients with localized disease is anatomical surgical resection, granting good average survival in the long term. We did not find Chilean studies focusing on complications, long term survival or potential association with pathological or clinical factors.
View Article and Find Full Text PDFPLoS One
January 2025
Jinan University, Guangzhou, China.
Objective: This study aimed to develop and validate a nomogram to predict the risk of sepsis in non-traumatic subarachnoid hemorrhage (SAH) patients using data from the MIMIC-IV database.
Methods: A total of 803 SAH patients meeting the inclusion criteria were randomly divided into a training set (563 cases) and a validation set (240 cases). Independent prognostic factors were identified through forward stepwise logistic regression, and a nomogram was created based on these factors.
JAMA Netw Open
January 2025
Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic, Rochester, Minnesota.
Importance: Understanding the interplay between diabetes risk factors and diabetes development is important to develop individual, practice, and population-level prevention strategies.
Objective: To evaluate the progression from normal and impaired fasting glucose levels to diabetes among adults.
Design, Setting, And Participants: This retrospective community-based cohort study used data from the Rochester Epidemiology Project, in Olmsted County, Minnesota, on 44 992 individuals with at least 2 fasting plasma glucose (FPG) measurements from January 1, 2005, to December 31, 2017.
Clin Exp Nephrol
January 2025
Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, 4000 Reservoir Rd NW, Washington, DC, 20007, USA.
This review article series on water and electrolyte disorders is based on the 'Electrolyte Winter Seminar' held annually for young nephrologists in Japan. The seminar features dynamic case-based discussions, some of which are included as self-assessment questions in this series. The second article in this series focuses on treatment of hyponatremia, a common water and electrolyte disorder frequently encountered in clinical practice.
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