A potential new use for gonadotropin-releasing hormone antagonists.

Objective: To describe a potential new use of gonadotropin-releasing hormone (GnRH) antagonists.

Design: Case report.

Setting: Assisted conception unit at a teaching hospital in the United Kingdom.

Patient(s): A 37-year-old woman undergoing in vitro fertilization (IVF) who accidentally stopped using GnRH agonists after starting ovarian stimulation.

Intervention(s): A GnRH antagonist was used to avoid a luteinizing hormone (LH) surge and hence "rescue" the cycle.

Result(s): Successful oocyte retrieval was carried out, two embryos transferred, and a viable twin pregnancy ensued.

Conclusion(s): This may be a new indication for the use of GnRH antagonists.