Unlabelled: Fatigue is a major problem among individuals diagnosed with multiple sclerosis (MS), but its meaning in daily living is unclear. The aim was to describe MS-related fatigue as lived by a group of individuals diagnosed with MS. Interviews with nine individuals were analysed from a phenomenological perspective.
Main Findings: MS-related fatigue is living with a time-consuming and all absorbing phenomenon, involving the body and the whole human being. Fatigue is commonly non-constructively perceived and expressed in terms of energy loss, emotional afflictions, dependency and restrictions of life in general, however, it is also constructively perceived and involves a desire to accept life and strive for a better situation.
Conclusion: MS-related fatigue is a comprehensive phenomenon and its relationship with self-care requires further investigation.
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http://dx.doi.org/10.1016/s0020-7489(03)00010-5 | DOI Listing |
Neuroscience
January 2025
Alliance for Research in Exercise, Nutrition and Activity (ARENA), Allied Health and Human Performance, University of South Australia, South Australia, Australia.
Physical and motor fatigue are debilitating symptoms common in multiple sclerosis (MS). Lifestyle interventions may be effective in managing MS-related fatigue. This scoping review aims to: (i) identify and summarise lifestyle interventions including those focused on diet, physical activity, and sleep, or multicomponent interventions for physical and motor fatigue management in MS; and (ii) provide recommendations for future research in this area.
View Article and Find Full Text PDFNeuroscience
December 2024
Department of Neurology, Oregon Health & Science University, Portland, OR, United States; APDM Precision Motion, Clario, Portland, Oregon, United States. Electronic address:
Fatigue in people with Multiple Sclerosis (PwMS) is a poorly understood, complex, and disabling symptom. We hypothesized that the perception of fatigue in PwMS results from increased information processing in cortical areas responsible for the perception of bodily states and decreased information processing in the cortico-basal ganglia network involved in the perception of motor performance. We investigated whether PwMS who perceive excessive fatigue would have increased resting-state functional connectivity (rsFC) between interoceptive brain areas (amygdala, anterior cingulate cortex [ACC], and insula) and decreased rsFC between cortico-basal ganglia premotor network compared to PwMS not reporting fatigue.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Neurology, King Abdulaziz Specialist Hospital, Taif 26521, Saudi Arabia.
: To evaluate the effect of bio-electromagnetic energy regulation (BEMER) therapy on erectile dysfunction (ED) in patients with multiple sclerosis (MS). A triple-blind randomized clinical trial was conducted in two different centers. Fifty-two male participants with MS were randomly allocated into two groups.
View Article and Find Full Text PDFInt J MS Care
October 2024
Institute for Neuroimmunology and Multiple Sclerosis, Universitätskklinikum Hamburg-Eppendorf, Hamburg, Germany.
Background: Fatigue is common in multiple sclerosis (MS); it significantly impairs quality of life, and treatment options are limited. A randomized controlled trial of Elevida, a self-guided, online German fatigue intervention, showed significant benefit. We tested an English version of Elevida with people with MS in Australia.
View Article and Find Full Text PDFMult Scler Relat Disord
December 2024
Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden; Women's Health and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Background: Fatigue is a subjective lack of physical and/or mental energy and is commonly perceived by people with multiple sclerosis (MS). People with MS often describe fatigue as the most troublesome MS related impairment, and it also has a negative impact on ability to initiate or maintain activities as well as work capacity and health related quality of life. The Modified Fatigue Impact Scale (MFIS) is a patient-reported outcome measurement of fatigue.
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