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Simultaneous Treatment of Two Severe Acute Intoxication and Acute Kidney Injury.
Semin Dial
December 2024
Nephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Extracorporeal therapies could be required for treatment of life-threatening severe acute intoxication. We present the case of an 82-year-old patient admitted to our Nephrology Unit because of metformin-associated lactic acidosis (MALA) and acute kidney injury (AKI stage III AKIN criteria). The patient also presented severe intoxication of digoxin and apixaban.
View Article and Find Full Text PDFUse of intravenous calcium in emergencies to treat patients with hyperkalemia and digoxin poisoning and its impact on short-term outcome.
Med Clin (Barc)
November 2024
Área de Urgencias, Hospital Clínic Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, España.
Objetives: Patients with digitalis intoxication (DI) and hyperkalaemia are frequently encountered in the emergency department (ED). This alteration may require intravenous (iv) calcium, but its administration has been considered to increase cardiotoxicity and mortality in patients with DI. We studied the effect of iv calcium on mortality and 30-day readmission in patients with hyperkalaemia and DI.
View Article and Find Full Text PDF[Severe intoxication after yew (Taxus) ingestion-case report and literature review].
Med Klin Intensivmed Notfmed
October 2024
Asklepios Klinik Altona, Abteilung für Kardiologie und internistische Intensivmedizin, Paul-Ehrlich-Str. 1, 22763, Hamburg, Deutschland.
Background: Severe yew (Taxus) intoxication is a rare condition that can lead to life-threatening cardiac arrhythmia. The survival of patients requires highly specialized emergency and intensive care treatment.
Objectives: Systematic overview of the clinical picture and important treatment options.
Antidote use for cardiac arrest or hemodynamic instability due to cardiac glycoside poisoning: A narrative review.
Resusc Plus
September 2024
CHU de Québec Research Center CHU de Québec - Université Laval, Quebec City, QC, Canada.
Introduction: Cardiac glycosides comprise medications such as digoxin and digitoxin, plants, and even certain toad venoms. Intoxication with cardiac glycosides can lead to hemodynamic instability and cardiac arrest. With this narrative review, our objective was to determine if any therapy used in a near-cardiac arrest state due to cardiac glycoside poisoning could improve survival with favourable functional and neurological outcomes.
View Article and Find Full Text PDFNot only Van Gogh: a case of BRASH syndrome with concomitant digoxin toxicity.
J Med Case Rep
June 2024
USD Poison Control Center, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Background: Bradycardia, renal failure, atrioventricular (AV) node blocking, shock, and hyperkalemia syndrome is a potentially life-threatening clinical condition characterized by bradycardia, renal failure, atrioventricular (AV) node blocking, shock, and hyperkalemia. It constitutes a vicious circle in which the accumulation of pharmacologically active compounds and hyperkalemia lead to hemodynamic instability and heart failure.
Case Presentation: A 66-year-old Caucasian female patient was admitted to the emergency department presenting with fatigue and bradycardia.
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