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Identification of Use Cases, Target Groups, and Motivations Around Adopting Smart Speakers for Health Care and Social Care Settings: Scoping Review.
JMIR AI
January 2025
Faculty of Social Science, Ruhr University Bochum, Bochum, Germany.
Background: Conversational agents (CAs) are finding increasing application in health and social care, not least due to their growing use in the home. Recent developments in artificial intelligence, machine learning, and natural language processing have enabled a variety of new uses for CAs. One type of CA that has received increasing attention recently is smart speakers.
View Article and Find Full Text PDFShort histological kaleidoscope - recent findings in histology. Part IV.
Rom J Morphol Embryol
November 2024
Discipline of Histology, Department of Morphological Sciences, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;
The paper provides an overview of the current understanding of different cells and structures' biology [e.g., blood-retinal barrier, Bruch membrane, Clara (club) cells, brush cells and tuft cells, Merkel cells, Hofbauer cells, cytokeratins], including their origin, structure, function, and role in disease pathogenesis, and of the latest findings in the medical literature concerning the paracortex of the lymph nodes.
View Article and Find Full Text PDFAdvancing Treatment Options for Merkel Cell Carcinoma: A Review of Tumor-Targeted Therapies.
Int J Mol Sci
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Department of Dermatology, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Although rare, Merkel cell carcinoma (MCC) is a highly aggressive and increasingly prevalent neuroendocrine cancer of the skin. While current interventions, including surgical resection, radiation, and immunotherapy have been employed in treating many patients, those who remain unresponsive to treatment are met with sparse alternatives and a grim prognosis. For this reason, it is of interest to expand the repertoire of available therapies for MCC patients who remain resistant to current primary interventions.
View Article and Find Full Text PDFTargeted Drug Delivery in Periorbital Non-Melanocytic Skin Malignancies.
Bioengineering (Basel)
October 2024
Department of Ophthalmology, University Hospital of Udine, p.le S. Maria della Misericordia 15, 33100 Udine, Italy.
Targeted drug delivery has emerged as a transformative approach in the treatment of periorbital skin malignancies, offering the potential for enhanced efficacy and reduced side effects compared to traditional therapies. This review provides a comprehensive overview of targeted therapies in the context of periorbital malignancies, including basal cell carcinoma, squamous cell carcinoma, sebaceous gland carcinoma, and Merkel cell carcinoma. It explores the mechanisms of action for various targeted therapies, such as monoclonal antibodies, small molecule inhibitors, and immunotherapies, and their applications in treating these malignancies.
View Article and Find Full Text PDFMetastatic tumours to the parotid: A 20-year single institutional experience with an emphasis on 14 unusual presentations.
Ann Diagn Pathol
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Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
The parotid gland is a rare site for distant metastasis. We aim to provide an overview of metastatic tumours to the parotid over the past 20 years, focusing on clinicopathological analysis of 14 rare diagnoses. To the best of our knowledge, we are the first group to present the most up-to-date and largest case series on unusual metastases to the parotid.
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