Calcium phosphate, fluoroapatine mineral, Ca5(PO4)3F, characterized by a strong reflex in interplanar distance d = 2.789 A, were identified in the tissue of retinoblastoma by x-ray destructive analysis. The strong reflex intensity and the respective fluoroapatite level in the tumor are the higher, the more malignant the tumor is. The malignancy degree is determined by histologic analysis of the tumor cellular composition after enucleation.
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