AI Article Synopsis
- A new technique is being developed to repair genetic mutations directly in human chromosomes using the cell's DNA repair machinery.
- Although this method is still in its early stages compared to other gene therapy techniques and faces ongoing challenges, it has the potential to effectively treat many inherited disorders.
- Researchers are actively exploring both the possibilities and the limitations of this controversial method.
Article Abstract
A technique that can direct the repair of a genetic mutation in a human chromosome using the DNA repair machinery of the cell is under development. Although this approach is not as mature as other forms of gene therapy and fundamental problems continue to arise, it promises to be the ultimate therapy for many inherited disorders. There is a continuing effort to understand the potential and the limitations of this controversial approach.
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| http://dx.doi.org/10.1038/nrg1156 | DOI Listing |
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