AI Article Synopsis
- Six Holstein calves experienced progressive exophthalmos while receiving daily injections of dexamethasone as part of a metabolic study.
- The control calves did not show any signs of exophthalmos, and other ocular examinations were normal.
- Postmortem findings revealed significant buildup of retrobulbar adipose tissue in the affected calves, suggesting that dexamethasone may be linked to this tissue accumulation and the resulting eye protrusion.
Article Abstract
Six Holstein calves were evaluated for progressive exophthalmos. The affected calves were receiving daily injections of dexamethasone (30 microg/kg subcutaneously twice daily) as part of a metabolic study. The control calves did not exhibit exophthalmos. The ocular examinations were normal except for the exophthalmos, which ranged from mild to marked in severity. Upon postmortem examination, marked deposition of retrobulbar adipose tissue was noted in the affected calves. Dexamethasone administration appears to increase deposition of retrobulbar adipose tissue resulting in a progressive exophthalmos.
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| http://dx.doi.org/10.1046/j.1463-5224.2003.00287.x | DOI Listing |
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