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EAES rapid guideline: surgical management of complicated diverticulitis - with ESCP participation.
Surg Endosc
December 2024
Cancer Center Amsterdam, Amsterdam, Netherlands.
Background: The surgical management of complicated diverticulitis varies across Europe. EAES members prioritized this topic to be addressed by a clinical practice guideline through an online questionnaire.
Objective: To develop evidence-informed clinical practice recommendations for key stakeholders involved in the treatment of complicated diverticulitis; to improve operative and perioperative outcomes, patient experience and quality of life through a systematic evidence-to-decision approach by a diverse, multidisciplinary panel.
Revisiting the Rytov approximation in diffuse optics and its applications for the inverse and forward problems.
Sci Rep
December 2024
Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
We propose an overview of the Rytov approximation in diffuse optics of biological tissues, for the inverse and forward problems. First, we show a physical interpretation of the Rytov approximation as a type of partial pathlength (named fluence rate partial pathlength) which is distinct from the usual partial pathlength for reflectance measurements. Second, we study the accuracy of the Rytov approximation for the calculation of Jacobians considering absorption perturbations and reflectance measurements.
View Article and Find Full Text PDFUsing AI to prevent the insect apocalypse: toward new environmental risk assessment procedures.
Curr Opin Insect Sci
December 2024
European Molecular Biology Laboratory, Heidelberg, Trust Genome Campus, Hinxton CB10 1SD, UK. Electronic address:
Insect populations are declining globally, with multiple potential drivers identified. However, experimental data are needed to understand their relative contributions. We highlight the sublethal effects of pesticides at field-relevant concentrations, often overlooked in standard environmental risk assessments (ERA), as significant contributors to these declines.
View Article and Find Full Text PDFApplication of zeolites for efficient tannery wastewater remediation.
Environ Sci Pollut Res Int
December 2024
Stazione Sperimentale Per L'industria Delle Pelli E Delle Materie Concianti S.R.L., 80143, Napoli, Italy.
Leather manufacturing is the process of converting raw animal hides or skins into finished leather. The complex industrial procedures result in a tanning effluent composed of chemical compounds with potentially hazardous impacts on humans and ecosystems. Among the traditional and efficient wastewater treatments, adsorption is an effective and well-known approach, able to manage a wide range of contaminants from wastewater.
View Article and Find Full Text PDFApplication of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma.
Arch Toxicol
December 2024
Division of Toxicology, Wageningen University and Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Systemic bile acid homeostasis plays an important role in human health. In this study, a physiologically based kinetic (PBK) model that includes microbial bile acid deconjugation and intestinal bile acid reuptake via the apical sodium-dependent bile acid transporter (ASBT) was applied to predict the systemic plasma bile acid concentrations in human upon oral treatment with the antibiotic tobramycin. Tobramycin was previously shown to inhibit intestinal deconjugation and reuptake of bile acids and to affect bile acid homeostasis upon oral exposure of rats.
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