Writers often introduce into fiction works characters who suffer from one disease or another. The purpose of this literary finesse is to enrich the intrigue or to create a favourable environment for the observation of a group of human beings. The introduction of the sick person sometimes offers a chance to warn against venereal diseases or alcoholism or an opportunity to critize medicine and doctors. The writers more exceptionally express visionary views on the future of medicine. This paper selects a few interesting examples of "imagined diseases".
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http://dx.doi.org/10.2143/AC.58.4.2005293 | DOI Listing |
Cell Mol Life Sci
January 2025
Univ. Lille, CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale Et Fonctionnelle, 59000, Lille, France.
Glycans are known to be fundamental for many cellular and physiological functions. Congenital disorders of glycosylation (CDG) currently encompassing over 160 subtypes, are characterized by glycan synthesis and/or processing defects. Despite the increasing number of CDG patients, therapeutic options remain very limited as our knowledge on glycan synthesis is fragmented.
View Article and Find Full Text PDFCan J Surg
January 2025
From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Levett); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Elkaim); the Department of Orthopaedic Surgery, McGill University, Jewish General Hospital, Montréal, Que. (Zukor, Huk, Antoniou)
Can J Surg
January 2025
From the Faculty of Medicine, Dalhousie University, Halifax, N.S. (Huo); the Department of Primary Education, School of Education, University of Ioannina, Ioannina, Greece (Kontouli); the Department of Diagnostic Radiology, Dalhousie University, Halifax, N.S. (Manos); the Department of Pathology, Dalhousie University, Halifax, N.S. (Xu, Fris); the Department of Urology, Dalhousie University, Halifax, N.S. (Chun); the Division of Thoracic Surgery, Department of Surgery, Dalhousie University, Halifax, N.S. (Wallace, French)
Background: There is a need to expand eligibility criteria for lung cancer screening beyond age and smoking history. In this study, we sought to assess whether light-or-never-smokers and heavy smokers differ in molecular and immunologic markers based on conventional lung cancer screening criteria.
Methods: We conducted a retrospective review of lung cancer cases from 2005 to 2018 at a tertiary Canadian institution.
Arch Dis Child Fetal Neonatal Ed
December 2024
Centre for Research in Epidemiology and Statistics Obstetrical Perinatal and Pediatric Epidemiology Research Team, Paris, Île-de-France, France.
Objective: The objective is to evaluate changes in survival to discharge of liveborn infants less than 32 weeks' gestational age (GA) in France, where the latest available data on very preterm survival at a national-level are from the EPIPAGE-2 cohort in 2011.
Design: Population-based cohort study.
Setting: Metropolitan France in 2011, 2015 and 2020.
EJHaem
December 2024
Pediatric Onco-Hematology Department Nancy University Hospital Nancy France.
Context: Mucopolysaccharidosis (MPS) requires urgent treatment to prevent neurological damage. While gene therapy holds promise for effectively treating these diseases with minimal toxicity, access remains limited for most patients. Consequently, advancing allogeneic hematopoietic stem cell transplantation (HSCT) for young children is crucial.
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