The age-dependent structure of the contingents treated conservatively at the local outpatient clinics (197 women aged 17-82 and 59 men aged 25-85) and patients subjected to operations of total endoprosthesis of the hip joint for coxarthrosis (663 women aged 19-89 and 304 men aged 22-82) was investigated. The structure of the indices under study was found to fluctuate with the average period length 10.7 years (sigma = 2.7 years), 8.2 years (sigma = 3.5 years), 7.3 days (sigma = 3.0 years), 9.5 years (sigma = 2.1 years) respectively. A comparison of the fluctuation curves of the age-dependent structure of the women treated conservatively and operated upon showed the coincidence of the maximums in 35, 43, 60, 65, 69, 74-74 years of age, in men--in 34-35, 41, 75-76. It can be supposed that the revealed age-dependent fluctuations of activity of the inflammatory process and the pain syndrome correspondingly might be considered as an element of the periodic disease in pathogenesis of degenerative-dystrophic lesions of the hip joint.

Download full-text PDF

Source

Publication Analysis

Top Keywords

sigma years
16
years sigma
12
age-dependent structure
8
treated conservatively
8
women aged
8
men aged
8
hip joint
8
years
8
years years
8
[biorhythmical characterization
4

Similar Publications

Understanding complex volcanic hydrosystems using a multi-tracer approach.

Sci Total Environ

January 2025

CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.

Climate change affects groundwater availability and residence times, necessitating a thorough understanding of aquifer characteristics to define sustainable yields, particularly in regions where water is heavily exploited. This study focuses on the Volvic volcanic aquifer (Chaîne des Puys, France), where groundwater recharge has decreased due to climate change, raising concerns about water use sustainability. To address these challenges, this work proposes a multi-tracer approach, based on hydrogeological monitoring, including the estimation of groundwater ages, major elements chemistry and water stable isotopes to better characterise this resource decrease and more peculiarly its origin and its impact on the environment that has never been addressed.

View Article and Find Full Text PDF

Background: Spinal muscular atrophy (SMA) is caused by reduced expression of survival motor neuron (SMN) protein. Previous studies indicated SMA causes not only lower motor neuron degeneration but also extensive brain involvement. This study aimed to investigate the changes of brain white matter and structural network using diffusion tensor imaging (DTI) in children with type 2 and 3 SMA.

View Article and Find Full Text PDF

Long term substantial impacts of historic Chlor-Alkali production as a newly recognized source of polyhalogenated carbazoles in aquatic environments.

J Environ Sci (China)

July 2025

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; Institute of Environment and Health, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Bottom sediments of the North American Great Lakes are characterized by a high loading (over 3,000 tonnes) of polyhalogenated carbazoles (PHCZs). The origin of this environmental contaminant loading is unclear. Here, we first examined PHCZs levels and profiles in sediment, lotus, and fish from the Ya-Er Lake (China) that has been under the influence of an obsolete chlor-alkali facility for forty years and discovered substantial PHCZs contamination.

View Article and Find Full Text PDF

Carotid-Femoral Pulse Wave Velocity in Children in South Africa: Reference Values for the Vicorder Device.

Angiology

January 2025

Family Center for Research with Ubuntu, Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa.

Atherosclerosis often starts in childhood, tracking to adulthood. In children, early vascular disease can be detected as arterial stiffness. Carotid-femoral pulse wave velocity is considered the non-invasive gold standard method for measuring arterial stiffness and widely accepted for use in children.

View Article and Find Full Text PDF

Long-term risks of gene therapy are not fully understood. In this study, we evaluated safety outcomes in 783 patients over more than 2,200 total patient-years of observation from 38 T cell therapy trials. The trials employed integrating gammaretroviral or lentiviral vectors to deliver engineered receptors to target HIV-1 infection or cancer.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!