There are many reports on the versatility of the fibular flap, but only a few studies have reported on the morbidity, and none on the nutritive perfusion, of the donor site. This study describes for the first time the quantitative investigation of nutritive perfusion at the donor site after osteomyo-cutaneous fibula transfer. Tissue nutrition of the lower leg was measured in 25 patients by micro-lightguide spectrophotometry and laser Doppler flowmetry. In a standardized examination, hemoglobin oxygenation and blood flow of the donor leg and the contralateral leg (intraindividual control) were measured at the nutritive region of the peroneal artery (I), posterior tibial artery (II), and anterior tibial artery (III). In the operated leg, blood flow was significantly reduced in region I with the sacrificed peroneal artery, and significantly increased in region II and III, probably for compensation (P = 0.03). Decreased hemoglobin oxygenation and blood flow of the peroneal region at the donor site were without significance in comparison to the control leg (P = 0.55 and P = 0.35, respectively). Decreased nutritive perfusion at the donor site was below the threshold of clinical manifestation, and supports the low donor site morbidity following fibular grafting.
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http://dx.doi.org/10.1002/micr.10143 | DOI Listing |
Indian J Urol
January 2025
Department of Urology and Renal Transplant, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Introduction: Pain at the buccal mucosal graft (BMG) harvest site in the immediate postoperative period is common and delays resumption of oral intake. This study compares the time for resumption of pain-free solid and liquid diets and postoperative pain scores at harvest site following the administration of inferior-alveolar nerve-block plus buccal-nerve block (IANB + BNB) versus placebo. We hypothesize that the intervention could decrease pain and aid in early food intake.
View Article and Find Full Text PDFNanoscale Adv
January 2025
Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology Kattankulathur Tamil Nadu 603203 India
Bone remodeling, a continuous process of resorption and formation, is essential for maintaining skeletal integrity and mineral balance. However, in cases of critical bone defects where the natural bone remodeling capacity is insufficient, medical intervention is necessary. Traditional bone grafts have limitations such as donor site morbidity and availability, driving the search for bioengineered scaffold alternatives.
View Article and Find Full Text PDFACS Appl Energy Mater
January 2025
School of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Organic solar cells (OSCs) are attracting significant attention due to their low cost, lightweight, and flexible nature. The introduction of nonfullerene acceptors (NFAs) has propelled OSC development into a transformative era. However, the limited availability of wide band gap polymer donors for NFAs poses a critical challenge, hindering further advancements.
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Department of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, UK.
Objectives: Assessment of age, sex and smoking-specific risk of cancer diagnosis and non-cancer mortality following primary care consultation for 15 new-onset symptoms.
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Nat Cancer
January 2025
Dept. of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.
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