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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375582PMC

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Article Synopsis
  • Diagonal earlobe crease (DELC) is being studied as a potential indicator of coronary artery disease (CAD) and its link to atrial fibrillation (AF).
  • In a study involving 669 patients under 65 with CAD, researchers found that those with DELC had a higher incidence of AF compared to those without it during a follow-up period of about 45 months.
  • The results suggest that the presence of DELC is associated with nearly double the risk of developing AF in CAD patients, highlighting its potential role in AF detection.
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Frank's sign (FS) refers to a diagonal skin fold between the tragus and the outer edge of the earlobe. FS has been identified as an independent variable in coronary artery disease (CAD). Young patients with FS and previous myocardial infarction are still rarely reported in clinical studies.

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Introduction: Cardiovascular risk factors such as obesity, type 2 diabetes, hypertension, smoking, and dyslipidemia enfold heart disease morbimortality. Diagonal earlobe crease has been proposed as a prognostic marker of extension and severity of illness in patients with acute coronary syndrome. But its usefulness remains unclear in patients with or without coronary disease.

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Objective: Aim: To analyse laboratory and biochemical features of the severe persistent course of asthma in patients with undifferentiated connective tissue dysplasia (UCTD) syndrome, and their phenotypic and visceral stigmas of dysembryogenesis.

Patients And Methods: Materials and Methods: We enrolled 60 male patients with asthma, aged from 23 to 62 years (mean age (46.83 ±0.

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Purpose: To investigate the clinical application value of diagonal earlobe crease (DELC) in patients with chest pain for the diagnosis of coronary heart disease (CHD) and to construct a risk model by multivariate logistic regression.

Patients And Methods: Our trial enrolled prospectively and consecutively 706 chest pain patients with suspected CHD between January 2021 to June 2023 from Chengde Central Hospital. According to coronary angiography results, they were categorized into the CHD (n=457) and non-CHD groups (n=249).

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