257 patients with multiple sclerosis (MS) participated in the study in Yaroslavl region. The main epidemiological indices (incidence and prevalence of MS) for the last 25 years were determined. The evaluation of environment pollution has been realized in different districts of the city according to the level of snow covering pollution. Farther in snow-test contents of 38 chemical elements found in industrial waste were determined and summary index of pollution of environment were calculated. Significant direct correlation is revealed between level of environment pollution and increasing of epidemiological characteristics of MS.

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