Objective: To estimate the degree of internal exposure to organochlorine pesticides (persistent organic pollutants, POP) among inhabitants of an open-air dump.
Methods: This was an observational study with simultaneous measurement and control, in which the criterion for subjects was that they dwelled in an area contaminated by POP and the effect of such contamination was the concentration of such substances into the blood. The study population consisted of 238 people living on an open-air dump in Pil es, in the municipality of Cubatão, SP, Brazil, and the control population was formed by 258 people, also resident in that municipality, in the Cota 200 district. The following pesticides were analysed: hexachlorobenzene (HCB), p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH (hexachlorocyclohexane); b HCH; g HCH; aldrin; dieldrin; endrin; heptachlor; heptachlor-epoxy and mirex.
Results: The average blood level of HCB in Pil es was 4.66 g/l, which was 155 times higher than the average for Cota 200 (0.03 g/l). In Pil es the average blood concentration of total DDT was 3.71 g/l, which was twice the level found in Cota 200 (1.85 g/l). Total HCH presented blood concentrations that were six times greater in Pil es (0.84 g/l versus 0.13 g/l).
Conclusions: A positive association was shown between dwelling in Pil es and the presence of POP in the blood, with much higher risks than in localities without the presence of these contaminants.
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http://dx.doi.org/10.1590/s0034-89102003000400018 | DOI Listing |
Radiat Prot Dosimetry
December 2024
Carrera de Física, Facultad de Ciencias Puras y Naturales, Universidad Mayor de San Andrés, Calle 27 Cota Cota, Campus Universitario, La Paz, Bolivia.
The ambient dose equivalent rate H*(10) was determined at various locations in the metropolitan area of the cities of La Paz and El Alto in Bolivia. A NaI(Tl) scintillation detector was employed to infer the gamma-ray fluence, and the fluence was transformed in dose rates by means of the appropriate coefficients. In this paper, a full methodology for the estimation of dose rates associated with gamma rays emitted from the ground (terrestrial radiation) and the atmosphere is developed from measurements made with the scintillator instrument.
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Friends of Cancer Research, Washington, DC.
Fungal Syst Evol
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Westerdijk Fungal Biodiversity Institute, P.O. Box 85167, 3508 AD Utrecht, The Netherlands.
Novel species of fungi described in this study include those from various countries as follows: , in leaves of , among deep leaf litter, from uredinium of on , on well-rotted twigs and litter in mixed wet sclerophyll and subtropical rainforest. , on twigs of , on bark, in savannas with shrubs and trees. , on leaves of , (incl.
View Article and Find Full Text PDFSci Rep
April 2024
Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Visceral leishmaniasis (VL) is an infectious disease caused by Leishmania infantum. Clinically, VL evolves with systemic impairment, immunosuppression and hyperactivation with hypergammaglobulinemia. Although renal involvement has been recognized, a dearth of understanding about the underlying mechanisms driving acute kidney injury (AKI) in VL remains.
View Article and Find Full Text PDFInvest New Drugs
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START Midwest, Grand Rapids, MI, USA.
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