The problems of assessment of aspiration (foreign bodies, stomach contents, food material) in forensic practical work are well-known, especially if 'suffocation due to aspiration' is considered to be the cause of death (or a concurrent cause of death). In the last 4 years (1998-2001) in the Department of Legal Medicine of the Free University, Berlin, 14 deaths with massive aspirations were investigated. The lethal aspiration cases consisted of seven men and five women between 55 and 91 years old, as well as two children (boy 6 years and girl 19 months old). All but one of the victims had severe neurological alterations (dementia, apoplexia, sequelae of head injuries). In six cases the victims died during or a short time after a meal; they had been fed by the nursing staff, a family member or another caregiver. The witness statements pertaining to clinical symptoms or the course of events ranged from 'no symptoms' to intensive cyanosis, congestion and no clear reactions of distress.
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http://dx.doi.org/10.1016/s1344-6223(02)00158-x | DOI Listing |
Am J Pathol
December 2024
Department of Periodontology, School of Dentistry, Aichi Gakuin University, Nagoya, Japan.
Periodontitis was reported to be associated with aspiration pneumonia. However, the relationship between periodontitis and aspiration pneumonia remains unclear. This study investigated the virulence factor of Porphyromonas gingivalis, which exacerbates aspiration pneumonia, and the role of IL-35, an inhibitory heterodimeric cytokine of EBI3 and p35, in aspiration pneumonia using Ebi3 knockout (KO) mice.
View Article and Find Full Text PDFCureus
October 2024
Department of Pathology and Forensic Medicine, Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, GEO.
Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a rare thyroid malignancy typically linked to chronic lymphocytic thyroiditis. We present the first documented case of SMECE in Georgia, involving a 41-year-old woman with Hashimoto's thyroiditis. A 16 mm hypoechoic thyroid nodule was detected on routine ultrasound, and fine needle aspiration categorized it as Bethesda V.
View Article and Find Full Text PDFForensic Sci Int
January 2025
Centre for Forensic Science, University of Technology Sydney, New South Wales, Australia.
'Where to from Here' (WTFH) was the theme chosen for the 2023 meeting of the International Association of Forensic Sciences (IAFS). This theme reflects the fact that forensic science is evolving rapidly, not only within individual sub-disciplines but, critically, across the whole forensic science landscape. Identifying and predicting evolutionary change will enable a more focused and constructive future for forensic science.
View Article and Find Full Text PDFJ Anal Toxicol
November 2024
Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto - Universidade de São Paulo, Ribeirão Preto, Brazil, CEP: 14040-901.
Novel psychoactive substances (NPS) continue to emerge in the marketplace and are often found as substances in traditional illicit drug materials, and users are often unaware of the presence of other drugs. The proper identification and confirmation of the exposure to a drug is made possible when a biological specimen is collected and tested. Sweat is an alternative biological matrix of great interest for clinical, and forensic analysis.
View Article and Find Full Text PDFJ Chromatogr A
December 2024
Key Laboratory of Drug Monitoring and Control of Zhejiang Province, National Narcotics Laboratory Zhejiang Regional Center, Hangzhou 310053, PR China. Electronic address:
Drug abuse is a social issue worldwide, and there is an increasing demand for on-site rapid detection of illicit drugs. In this study, a rapid and simple analytical method for the detection of 6-monoacetylmorphine (6-MAM), methamphetamine (MA), methylenedioxymethamphetamine (MDMA), ketamine (K), norketamine (NK), and cocaine (COC) in urine was developed. The developed method combines C18 pipette-tip based solid-phase extraction (C18 PT-SPE) with a miniaturized mass spectrometer (miniMS), exhibiting remarkable simplicity, high sensitivity, and strong reliability, compared with the conventional method.
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